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基于分数阶紧致有限差分格式的非局部均值去噪算法有效降低光学相干断层扫描图像中的斑点噪声。

Non-Local Mean Denoising Algorithm Based on Fractional Compact Finite Difference Scheme Effectively Reduces Speckle Noise in Optical Coherence Tomography Images.

作者信息

Chen Huaiguang, Gao Jing

机构信息

School of Science, Shandong Jianzhu University, Jinan 250101, China.

Center for Engineering Computation and Software Development, Shandong Jianzhu University, Jinan 250101, China.

出版信息

Micromachines (Basel). 2022 Nov 22;13(12):2039. doi: 10.3390/mi13122039.

DOI:10.3390/mi13122039
PMID:36557339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9781262/
Abstract

Optical coherence tomography (OCT) is used in various fields such, as medical diagnosis and material inspection, as a non-invasive and high-resolution optical imaging modality. However, an OCT image is damaged by speckle noise during its generation, thus reducing the image quality. To address this problem, a non-local means (NLM) algorithm based on the fractional compact finite difference scheme (FCFDS) is proposed to remove the speckle noise in OCT images. FCFDS uses more local pixel information when compared to integer-order difference operators. The FCFDS operator is introduced into the NLM algorithm to construct a high-precision weight calculation so that the proposed algorithm can effectively reduce the speckle noise in the OCT images. Experiments on simulations and real OCT images show that the proposed method is comparable to other state-of-the-art despeckling methods and can substantially reduce noise and preserve image details such as edges and structures. Speckle noise removal can further promote the application of the proposed algorithm in medical diagnosis and industrial detection, as it has key research value.

摘要

光学相干断层扫描(OCT)作为一种非侵入性的高分辨率光学成像方式,被应用于医学诊断和材料检测等各个领域。然而,OCT图像在生成过程中会受到散斑噪声的影响,从而降低图像质量。为了解决这个问题,提出了一种基于分数紧致有限差分格式(FCFDS)的非局部均值(NLM)算法来去除OCT图像中的散斑噪声。与整数阶差分算子相比,FCFDS使用了更多的局部像素信息。将FCFDS算子引入NLM算法中,构建高精度的权重计算,使得所提出的算法能够有效降低OCT图像中的散斑噪声。对模拟图像和实际OCT图像的实验表明,该方法与其他现有去噪方法相当,能够大幅降低噪声并保留边缘和结构等图像细节。散斑噪声去除可以进一步推动所提出算法在医学诊断和工业检测中的应用,具有关键的研究价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/d830035bbe1d/micromachines-13-02039-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/b27e0d5e7c8c/micromachines-13-02039-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/e19b7fac53aa/micromachines-13-02039-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/0a7b62b4f4a1/micromachines-13-02039-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/145a3a055730/micromachines-13-02039-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/e7aa34b6cd98/micromachines-13-02039-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/d830035bbe1d/micromachines-13-02039-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/b27e0d5e7c8c/micromachines-13-02039-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/e19b7fac53aa/micromachines-13-02039-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/0a7b62b4f4a1/micromachines-13-02039-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/145a3a055730/micromachines-13-02039-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/e7aa34b6cd98/micromachines-13-02039-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e003/9781262/d830035bbe1d/micromachines-13-02039-g006.jpg

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本文引用的文献

1
Triplet Cross-Fusion Learning for Unpaired Image Denoising in Optical Coherence Tomography.三重交叉融合学习在光学相干断层扫描中的未配对图像去噪。
IEEE Trans Med Imaging. 2022 Nov;41(11):3357-3372. doi: 10.1109/TMI.2022.3184529. Epub 2022 Oct 27.
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Denoising algorithm of OCT images via sparse representation based on noise estimation and global dictionary.基于噪声估计和全局字典的 OCT 图像稀疏表示去噪算法。
Opt Express. 2022 Feb 14;30(4):5788-5802. doi: 10.1364/OE.447668.
3
Guided filtering-based nonlocal means despeckling of optical coherence tomography images.
基于导向滤波的光学相干断层扫描图像的非局部均值去噪。
Opt Lett. 2020 Oct 1;45(19):5600-5603. doi: 10.1364/OL.400926.
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Comput Methods Programs Biomed. 2020 Nov;196:105670. doi: 10.1016/j.cmpb.2020.105670. Epub 2020 Jul 21.
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Temporal speckle-averaging of optical coherence tomography volumes for cellular resolution neuronal and vascular retinal imaging.用于细胞分辨率神经元和视网膜血管成像的光学相干断层扫描容积的时间散斑平均法
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BM3D-based total variation algorithm for speckle removal with structure-preserving in OCT images.基于BM3D的全变差算法在光学相干断层扫描(OCT)图像中去除散斑并保留结构。
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Aperture phase modulation with adaptive optics: a novel approach for speckle reduction and structure extraction in optical coherence tomography.基于自适应光学的孔径相位调制:光学相干断层扫描中减少散斑和提取结构的新方法。
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