Arcos A, Serramito R, Santín J M, Prieto A, Gelabert M, Rodriguez-Osorio X, Reyes R
Departments of Neurosurgery, University of Santiago de Compostela, Spain.
Neurocirugia (Astur). 2010 Dec;21(6):461-6. doi: 10.1016/s1130-1473(10)70098-1.
Meningioangiomatosis (MA) is a rare, benign neoplastic disorder involving the cortex and leptomeninges, the sporadic form, commonly presents as refractory localization-related epilepsy, but could be asymptomatic especially in older patients. The imaging features may be entirely non-specific. Magnetic Resonance Imaging (MRI) erroneously suggests meningioma, lowgrade tumour or vascular malformations. The pathological findings are characterised by proliferation of meningothelial cells and leptomeningeal vessels and calcifications within the mass. Macroscopically there is dense thickening in the underlying cortex, often in a sharply defined area. In this article we report 3 cases of MA, neither of whom had a familiary history or stigmata of Neurofibromatosis (NF). We discuss and place particular emphasis on the clinical presentation and diagnosis imaging, as well as on the outcome. We also review the literature concerning about the aetiology, pathology findings and imaging features of MA.
脑膜血管外皮细胞瘤（MA）是一种罕见的良性肿瘤性疾病，累及皮质和软脑膜，散发性形式通常表现为难治性局灶性癫痫，但可能无症状，尤其是在老年患者中。其影像学特征可能完全不具特异性。磁共振成像（MRI）错误地提示为脑膜瘤、低级别肿瘤或血管畸形。病理表现为脑膜内皮细胞、软脑膜血管增生以及肿块内钙化。大体上，其下方皮质有致密增厚，通常在一个边界清晰的区域。在本文中，我们报告了3例MA病例，均无神经纤维瘤病（NF）家族史或体征。我们讨论并特别强调了临床表现、诊断性影像学以及预后。我们还回顾了有关MA的病因、病理表现和影像学特征的文献。
