Jamil Osama, Ramkissoon Shakti, Folkerth Rebecca, Smith Edward
Department of Neurosurgery, Children’s Hospital Boston, 300 Longwood Avenue,Boston, Massachusetts 02115, USA.
J Neurosurg Pediatr. 2012 Dec;10(6):486-9. doi: 10.3171/2012.9.PEDS1224. Epub 2012 Sep 28.
Meningioangiomatosis consists of benign hamartomatous lesions of the brain and the leptomeninges, which typically present with seizure. Management is predicated on resection and control of seizures with medication. Lesions are typically solitary. Multifocal meningioangiomatosis is extremely rare, with only 2 cases reported in adults and none in children. The authors report the first case, to their knowledge, of multifocal meningioangiomatosis in a child. This unique case highlights therapeutic challenges associated with these lesions and demonstrates that multifocality is possible in the pediatric population. This finding has implications for diagnosis and follow-up for children afflicted with these tumors.
脑膜血管外皮细胞瘤病由大脑和软脑膜的良性错构瘤性病变组成，通常表现为癫痫发作。治疗方法是手术切除并通过药物控制癫痫发作。病变通常为单发。多灶性脑膜血管外皮细胞瘤病极为罕见，成人仅报告过2例，儿童尚无病例报告。据作者所知，本文报告了首例儿童多灶性脑膜血管外皮细胞瘤病。这一独特病例凸显了与这些病变相关的治疗挑战，并表明多灶性在儿童人群中是可能的。这一发现对患有这些肿瘤的儿童的诊断和随访具有重要意义。
