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保乳治疗后因放射治疗导致的纤维化行部分乳房切除术和背阔肌重建。

Partial mastectomy and m. latissimus dorsi reconstruction for radiation-induced fibrosis after breast-conserving cancer therapy.

机构信息

Department of Surgical Oncology, Erasmus Medical Center/Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, Netherlands.

出版信息

World J Surg. 2011 Mar;35(3):568-72. doi: 10.1007/s00268-010-0911-8.

DOI:10.1007/s00268-010-0911-8
PMID:21165619
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3032904/
Abstract

BACKGROUND

Patients with severe complaints of radiation-induced fibrosis after breast-conserving therapy and not responding to conservative therapy, were treated by partial mastectomy and m. latissimus dorsi reconstruction.

METHOD

To determine the feasibility and outcome of this approach, a retrospective study of nine patients was carried out.

RESULTS

After a mean follow-up of 46 months, eight of the nine patients experienced improvement of their complaints and shape of the breast. In only one case did the procedure fail, as evidenced by continuation of all complaints.

CONCLUSIONS

Partial mastectomy and m. latissimus dorsi reconstruction is the ultimate option in the treatment of radiation fibrosis. The procedure is safe with satisfying results.

摘要

背景

对于接受保乳治疗后出现严重放射性纤维化且保守治疗无效的患者,可采用部分乳房切除术和背阔肌重建术进行治疗。

方法

为了确定这种方法的可行性和效果,我们对 9 例患者进行了回顾性研究。

结果

平均随访 46 个月后,9 例患者中有 8 例的症状和乳房形状均得到改善。只有 1 例手术失败,所有症状均持续存在。

结论

部分乳房切除术和背阔肌重建术是治疗放射性纤维化的最终选择。该手术安全,效果满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/724a/3032904/0ec44f5c1bda/268_2010_911_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/724a/3032904/0ec44f5c1bda/268_2010_911_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/724a/3032904/0ec44f5c1bda/268_2010_911_Fig1_HTML.jpg

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本文引用的文献

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Breast J. 2009 Nov-Dec;15(6):583-92. doi: 10.1111/j.1524-4741.2009.00835.x. Epub 2009 Oct 12.
2
Postmastectomy reconstruction of the breast using the latissimus dorsi musculocutaneous flap.采用背阔肌肌皮瓣进行乳房切除术后乳房重建。
Cancer J. 2008 Jul-Aug;14(4):248-52. doi: 10.1097/PPO.0b013e318180bcc2.
3
Oncoplastic breast-conserving surgery: analysis of quadrantectomy and immediate reconstruction with latissimus dorsi flap.
慢性放射性皮炎:挑战与解决方案
Clin Cosmet Investig Dermatol. 2016 Dec 9;9:473-482. doi: 10.2147/CCID.S94320. eCollection 2016.
4
Percutaneous irreversible electroporation for breast tissue and breast cancer: safety, feasibility, skin effects and radiologic-pathologic correlation in an animal study.经皮不可逆电穿孔用于乳腺组织和乳腺癌:一项动物研究中的安全性、可行性、皮肤效应及放射学与病理学相关性
J Transl Med. 2016 Aug 5;14(1):238. doi: 10.1186/s12967-016-0993-7.
肿瘤整形保乳手术:背阔肌肌皮瓣象限切除术及即刻重建分析
World J Surg. 2007 Oct;31(10):1934-40. doi: 10.1007/s00268-007-9196-y.
4
The role of the latissimus dorsi flap in reconstruction of the irradiated breast.
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