Jumao-as A, Brenner R P
Department of Neurology, University of Pittsburgh School of Medicine, PA.
Neurology. 1990 Aug;40(8):1199-202. doi: 10.1212/wnl.40.8.1199.
We reviewed the clinical features and ictal EEGs in 23 adults with myoclonic status epilepticus (MSE). Anoxic encephalopathy was the most common cause of MSE, occurring in 15 patients; 8 developed MSE within 14 hours following the anoxic insult. Metabolic encephalopathies were present in 4 patients, while 2 had degenerative CNS disorders. In 2 patients with generalized epilepsy, MSE developed during a medication change. Five types of EEG patterns were associated with MSE. Generalized periodic complexes (usually spikes, polyspikes, or sharp waves), often with attenuation of background activity between complexes (11 patients) or a burst-suppression pattern (4 patients), were the most common types. Outcome was poor: 20 patients died without regaining consciousness, while 1 remains in a vegetative state. The 2 patients with generalized epilepsy, both of whom were conscious during MSE, survived without sequelae.
我们回顾了23例成人肌阵挛性癫痫持续状态（MSE）患者的临床特征和发作期脑电图。缺氧性脑病是MSE最常见的病因，15例患者出现该病因；其中8例在缺氧性损伤后14小时内发生MSE。4例患者存在代谢性脑病，2例患有中枢神经系统退行性疾病。2例全身性癫痫患者在药物更换期间发生MSE。五种脑电图模式与MSE相关。全身性周期性复合波（通常为棘波、多棘波或锐波），常伴有复合波之间背景活动减弱（11例患者）或爆发抑制模式（4例患者），是最常见的类型。预后较差：20例患者死亡且未恢复意识，1例仍处于植物人状态。2例全身性癫痫患者在MSE期间均有意识，存活且无后遗症。
