Department of Psychiatry, St Michael's Hospital, Toronto, Ontario, Canada.
BMC Geriatr. 2010 Dec 17;10:89. doi: 10.1186/1471-2318-10-89.
Medical co-morbidity may be associated with impaired cognitive function based on prior studies. However, no studies to date have determined to what extent this association is linked to medical illness or other factors that may be linked to medical illness (such as education, income levels, depression or subjective memory loss). The present study examined how medical co-morbidity, socioeconomic status (defined as residential SES), education and depression are associated with subjective and objective memory function in a sample of patients recruited from a university affiliated Memory Disorders Clinic located in a large Canadian inner city teaching hospital.
Data was collected from 85 consecutive referrals to an Inner City Memory Disorders Clinic including socio-demographic characteristics, cognitive status and medical co-morbidity. Descriptive and correlational analyses were conducted.
Impaired objective cognitive function correlated significantly with increased medical co-morbidity and partially with education but not with residential SES or depression. Elevated memory complaints correlated significantly with depression, inversely with residential SES and not at all with medical co-morbidity or education.
Increased medical co-morbidity is significantly associated with impaired cognitive performance but not with subjective memory complaints in an Inner City Memory Clinic sample.
基于先前的研究，医学合并症可能与认知功能受损有关。然而，迄今为止尚无研究确定这种关联在多大程度上与疾病本身或其他可能与疾病相关的因素（如教育、收入水平、抑郁或主观记忆丧失）有关。本研究在一个位于加拿大大型城市教学医院的大学附属医院记忆障碍诊所招募的患者样本中，检查了医学合并症、社会经济地位（定义为居住社会经济地位）、教育和抑郁与主观和客观记忆功能的关系。
从 85 例连续转诊至市区记忆障碍诊所的患者中收集了社会人口统计学特征、认知状况和医学合并症的数据。进行了描述性和相关性分析。
客观认知功能障碍与合并症增多显著相关，部分与教育相关，而与居住社会经济地位或抑郁无关。记忆力主诉升高与抑郁显著相关，与居住社会经济地位呈负相关，与医学合并症或教育无关。
在市区记忆障碍诊所的样本中，合并症增多与认知功能障碍显著相关，但与主观记忆主诉无关。
