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[胰腺结核:腹痛和发热的一个意想不到的病因]

[Tuberculosis of the pancreas: an unsuspected cause of abdominal pain and fever].

作者信息

Suárez-Moreno Roberto Manuel, Hernández-Ramírez Daniel Alejandro, Madrazo-Navarro Mario, Salazar-Lozano Carlos Rafael, García-Álvarez Karla Gisela, Espinoza-Álvarez Arturo

机构信息

Dirección Médica, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D. F., Mexico.

出版信息

Cir Cir. 2010 Jul-Aug;78(4):352-6.

Abstract

BACKGROUND

Tuberculosis is frequently the form of presentation of human immunodeficiency virus (HIV) infection even in patients who have not developed acquired immune deficiency syndrome (AIDS). Nevertheless, pancreatic affection is uncommon. Tuberculosis of the pancreas (TBP) is a clinical rarity and mimics pancreatic carcinoma both clinically and radiologically.

CLINICAL CASE

We present the case of a 42-year-old man with a 5-day evolution of moderate abdominal pain in the right lower quadrant and fever and vomiting without diarrhea. The patient had no history of abdominal surgery. CT scan revealed a heterogeneously enhancing, multicystic structure in the pancreatic head. Due to suspicion of malignancy, a pancreatoduodenectomy was performed with pathological result of pancreatic tuberculosis. The patient was discharged on the 10th postoperative day without surgical complications. He died 10 months later of Pneumocystis jirovecii pneumonia. By that time he had a positive serum HIV antibodies test.

CONCLUSIONS

TBP diagnosis can be missed or significantly delayed because it is often not suspected prior to laparotomy unless there is evidence of pulmonary tuberculosis. TBP should be considered in the differential diagnosis of a mass in the head of the pancreas. The response to early antituberculosis treatment is very effective.

摘要

背景

即使在尚未发展为获得性免疫缺陷综合征(AIDS)的人类免疫缺陷病毒(HIV)感染患者中,结核病也常常是其表现形式。然而,胰腺受累并不常见。胰腺结核(TBP)在临床上较为罕见,在临床和影像学上都与胰腺癌相似。

临床病例

我们报告一例42岁男性患者,右下腹部中度腹痛伴发热和呕吐5天,无腹泻。患者无腹部手术史。CT扫描显示胰头部有一个不均匀强化的多囊结构。由于怀疑为恶性肿瘤,遂行胰十二指肠切除术,病理结果为胰腺结核。患者术后第10天出院,无手术并发症。10个月后,他死于耶氏肺孢子菌肺炎。那时他的血清HIV抗体检测呈阳性。

结论

由于除非有肺结核证据,否则在剖腹手术前通常不会怀疑TBP,因此其诊断可能会被漏诊或显著延迟。在胰腺头部肿块的鉴别诊断中应考虑TBP。早期抗结核治疗的反应非常有效。

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