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[研究KBP - 2010 - CPHG:纳入2010年1月1日至12月31日期间在综合医院肺病科诊断出的原发性肺癌新病例]

[Study KBP-2010-CPHG: inclusion of new cases of primary lung cancer diagnosed in general hospital pneumology departments between 1st January and 31 December 2010].

作者信息

Grivaux M, Locher C, Bombaron P, Collon T, Coëtmeur D, Dayen C, Debieuvre D, Goupil F, Le Treut J, Martin F, Molinier O, Asselain B, Zureik M, Blanchon F

机构信息

Service de pneumologie, centre hospitalier de Meaux, 6-8 rue Saint-Fiacre, BP 218, 77104 Meaux cedex, France.

出版信息

Rev Pneumol Clin. 2010 Dec;66(6):375-82. doi: 10.1016/j.pneumo.2010.08.001. Epub 2010 Dec 3.

Abstract

INTRODUCTION

The College of General Hospital Respiratory Physicians (CPHG) is following up the KBP-2000-CPHG study, performed ten years ago, with a new observational epidemiological study of primary lung cancer.

PATIENTS AND METHODS

The study includes all new cases of primary lung cancer diagnosed on histology or cytology between 1 January and 31 December 2010 and managed by one of the general hospital pneumology departments participating in the study. The primary objective is to estimate five-year mortality and to analyze risk factors. Secondary objectives are to describe the characteristics of this patient population and their management, and to estimate one, four and five-year survival rates. These data will be compared to those of the KBP-2000-CPHG study. The four-year prognosis score developed in 2000 will also be assessed in the new study. Data are collected by standardized questionnaire with exhaustiveness control.

EXPECTED RESULTS

One hundred and eight investigating centers have agreed to participate; 4000 to 5000 new cases of primary lung cancer should be collected and analyzed.

CONCLUSION

The study will describe the characteristics of patients presenting with primary lung cancer in the participating pneumology departments during the year 2010, and their diagnostic and therapeutic management, and assess changes over the last ten years.

摘要

引言

综合医院呼吸内科医师学会(CPHG)正在对十年前开展的KBP - 2000 - CPHG研究进行跟进,开展一项关于原发性肺癌的新的观察性流行病学研究。

患者与方法

该研究纳入了2010年1月1日至12月31日期间经组织学或细胞学诊断为原发性肺癌且由参与研究的综合医院呼吸内科之一进行管理的所有新病例。主要目标是估计五年死亡率并分析风险因素。次要目标是描述该患者群体的特征及其治疗情况,并估计一年、四年和五年生存率。这些数据将与KBP - 2000 - CPHG研究的数据进行比较。2000年制定的四年预后评分也将在新研究中进行评估。通过具有详尽性控制的标准化问卷收集数据。

预期结果

108个研究中心已同意参与;预计将收集并分析4000至5000例原发性肺癌新病例。

结论

该研究将描述2010年参与研究的呼吸内科中原发性肺癌患者的特征、他们的诊断和治疗情况,并评估过去十年间的变化。

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