Department of Surgery and Surgical Oncology, Helios Hospital, Berlin, Germany.
J Thorac Cardiovasc Surg. 2011 May;141(5):1213-7. doi: 10.1016/j.jtcvs.2010.07.096. Epub 2010 Dec 16.
Esophageal anastomotic leaks, perforations, and fistulae are associated with considerable morbidity and mortality. The aim of the present study was to assess the efficacy of self-expanding plastic stents in the treatment of esophageal leaks.
From 2001 to 2009, 41 patients with postoperative anastomotic leaks (n = 30), esophageal perforations (n = 6), or fistulae (n = 5) were treated by endoscopic insertion of self-expanding plastic stents. The clinical outcome of the patients was analyzed, including leak healing, morbidity, and mortality.
Self-expanding plastic stents were successfully inserted in all 41 patients without procedure-related complications. Non-ventilated patients received oral feeding an average of 3.9 days after stent placement. Complete leak healing was obtained in 27 of 30 patients (90%) with anastomotic leaks and 5 patients (83%) with perforation. Sealing of fistulae by the stents was achieved in all 5 patients, and closure of the fistula was observed in 2 patients (40%). The mean healing time was 30 days for anastomotic leaks, 15 days for esophageal perforations, and 16 days for fistulae. Stent migration occurred in 14 cases, but endoscopic reintervention and new stent placement were successful in all cases. In-hospital mortality after treatment of esophageal leaks with stents was 10%.
In combination with effective interventional or surgical drainage, stenting is a viable option for the treatment of esophageal anastomotic leaks and perforations, but the success in tracheoesophageal fistula is limited.
食管吻合口漏、穿孔和瘘与相当大的发病率和死亡率相关。本研究旨在评估自膨式塑料支架治疗食管漏的疗效。
2001 年至 2009 年,41 例术后吻合口漏(n=30)、食管穿孔(n=6)或瘘(n=5)患者通过内镜插入自膨式塑料支架进行治疗。分析患者的临床结果,包括漏口愈合、发病率和死亡率。
所有 41 例患者均成功插入自膨式塑料支架,无与操作相关的并发症。未通气的患者在支架放置后平均 3.9 天开始口服喂养。30 例吻合口漏患者中有 27 例(90%)和 5 例穿孔患者(83%)完全愈合。支架成功封堵所有 5 例瘘,2 例(40%)观察到瘘口闭合。吻合口漏的平均愈合时间为 30 天,食管穿孔为 15 天,瘘为 16 天。支架迁移发生在 14 例,但所有病例均通过内镜再次干预和新支架放置成功。支架治疗食管漏的住院死亡率为 10%。
与有效的介入或手术引流相结合,支架治疗是治疗食管吻合口漏和穿孔的可行选择,但在气管食管瘘中的疗效有限。