Anikhindi Shrihari Anil, Ranjan Piyush, Sachdeva Munish, Kumar Mandhir
Institute of Liver, Gastroenterology, and Pancreaticobiliary Sciences, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110 060, India.
Indian J Gastroenterol. 2016 Jul;35(4):287-93. doi: 10.1007/s12664-016-0679-3. Epub 2016 Aug 4.
Self-expanding plastic stents (SEPS) have emerged as a good alternative to surgery in esophageal leaks and fistulae. There is scarce published literature regarding its efficacy in these conditions. We present our experience with SEPS in treatment of esophageal leaks and fistulae.
Consecutive patients admitted in a tertiary referral center who underwent SEPS placement for esophageal leak or fistula between February 2012 and February 2015 were retrospectively evaluated. Patients underwent prior assessment with upper gastrointestinal endoscopic and thoracic contrast-enhanced computed tomography assessment. SEPS (25-mm flares, 21-mm diameter) were placed under fluoroscopic guidance. A silk thread tied to upper end was routed through nostril and fixed to prevent stent migration. Nasojejunal tube was inserted in all patients. Intercostal drain was inserted in the case of hydro/pyopneumothorax.
Twelve patients [eight male, median age 45.3 years (19 to 65 years)] were included. Etiologies were spontaneous leaks due to Boerhaave syndrome (n = 2), corrosive fistulae (n = 2), tubercular fistulae (n = 4), invasive Candida esophagitis-induced fistula (n = 1), iatrogenic leaks (n = 2; one achalasia dilatation, one obesity surgery), and pancreaticoesophageal fistula due to ruptured pancreatic pseudocyst (n = 1). Stent placement was successful in all patients with no immediate postprocedure complications. Successful healing was seen in nine patients (75 %). Stents were removed after a median time of 83.5 days (13-190 days). Stent migration was seen in four patients (33.3 %), and in two of them, it was retrieved and redeployed; none had early migration (<72 h). Reasons for SEPS failure in our cohort were failure of effective sepsis control in two patients and poor wound healing seen in one patient having multiple tubercular fistulae.
SEPS is a safe, well-tolerated treatment with good success rate (75 %) in treatment of esophageal leaks and fistulae.
自膨式塑料支架(SEPS)已成为食管漏和瘘手术的良好替代方案。关于其在这些情况下疗效的已发表文献很少。我们介绍我们使用SEPS治疗食管漏和瘘的经验。
对2012年2月至2015年2月在三级转诊中心因食管漏或瘘接受SEPS置入的连续患者进行回顾性评估。患者术前接受上消化道内镜和胸部增强CT评估。SEPS(25毫米喇叭口,21毫米直径)在荧光透视引导下置入。一根系在上端的丝线经鼻孔引出并固定以防止支架移位。所有患者均插入鼻空肠管。如有液气胸或脓气胸则插入肋间引流管。
纳入12例患者[8例男性,中位年龄45.3岁(19至65岁)]。病因包括博雷尔综合征导致的自发性漏(n = 2)、腐蚀性瘘(n = 2)、结核性瘘(n = 4)、侵袭性念珠菌食管炎引起的瘘(n = 1)、医源性漏(n = 2;1例贲门失弛缓症扩张,1例肥胖症手术)以及胰腺假性囊肿破裂导致的胰食管瘘(n = 1)。所有患者支架置入均成功,术后无即刻并发症。9例患者(75%)愈合成功。支架在中位时间83.5天(13至190天)后取出。4例患者(33.3%)出现支架移位,其中2例支架被取出并重新置入;均无早期移位(<72小时)。我们队列中SEPS失败的原因是2例患者有效控制败血症失败,1例有多个结核性瘘的患者伤口愈合不良。
SEPS是一种安全、耐受性良好的治疗方法,治疗食管漏和瘘的成功率较高(75%)。