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食管支架治疗吻合口漏和穿孔。

Esophageal stents for anastomotic leaks and perforations.

机构信息

Division of Thoracic and Foregut Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minn 55455, USA.

出版信息

J Thorac Cardiovasc Surg. 2011 Jul;142(1):39-46.e1. doi: 10.1016/j.jtcvs.2011.04.027.

Abstract

OBJECTIVE

Intrathoracic esophageal anastomotic leaks and perforations are very morbid and challenging problems. Esophageal stents are increasingly playing an integral role in the management of these patients. Our objective was to report our experience with esophageal stent placement for anastomotic leaks and perforations and to provide a treatment algorithm.

METHODS

We performed a review of patients with stent placement for esophagogastric anastomotic leaks or esophageal perforation from March 2005 to August 2009. A prospective database was used to collect data. Success was defined as endoscopic defect closure, negative esophagram, and resumption of oral intake. Failure was defined as no change in leak size or clinical signs of ongoing infection. We collected and analyzed patient demographics, diagnosis, clinical history, and poststent outcomes using descriptive statistics.

RESULTS

Thirty-seven patients underwent esophageal stent placement for anastomotic leaks (n = 22) and perforations (n = 15). The median time from original procedure to diagnosis of leak or perforation was 6 days (0-420 days). Nineteen patients (51%) had 21 associated procedures for source control. We placed 94 stents (mean = 2.7 stents/patient); 16 patients (43%) required more than 1 stenting procedure (mean = 1.8 procedures/patient). The median time to restoration of esophageal integrity was 33 days (7-120 days). There were 22 successes (59%); 2 failures were secondary to undrained abscess. Only 2 failures occurred in the last 15 patients (88% success). Strictures did not develop in any patients. Serious complications occurred in 3 patients (stent erosion, leak enlargement, fatal gastroaortic fistula).

CONCLUSIONS

Esophageal stents can potentially play an integral role in the management of anastomotic leaks and perforations. Success depends on appropriate procedures for source control and surgeon experience.

摘要

目的

胸内食管吻合口漏和穿孔是非常严重和具有挑战性的问题。食管支架在这些患者的治疗中越来越发挥重要作用。我们的目的是报告食管支架置入治疗吻合口漏和穿孔的经验,并提供治疗方案。

方法

我们回顾了 2005 年 3 月至 2009 年 8 月间因食管胃吻合口漏或食管穿孔而行支架置入的患者。使用前瞻性数据库收集数据。成功定义为内镜下缺损闭合、食管造影阴性和恢复口服摄入。失败定义为漏口大小无变化或持续感染的临床体征无变化。我们使用描述性统计方法收集和分析患者的人口统计学、诊断、临床病史和支架置入后的结果。

结果

37 例患者因吻合口漏(n=22)和穿孔(n=15)而行食管支架置入。从初次手术到诊断漏口或穿孔的中位时间为 6 天(0-420 天)。19 例(51%)患者有 21 例相关手术用于控制源。我们共放置了 94 个支架(平均每个患者 2.7 个支架);16 例(43%)需要不止一次支架置入(平均每个患者 1.8 次)。恢复食管完整性的中位时间为 33 天(7-120 天)。22 例(59%)成功;2 例失败是由于未引流脓肿。在最后 15 例患者中仅发生 2 例失败(88%的成功率)。没有患者发生狭窄。3 例患者发生严重并发症(支架侵蚀、漏口扩大、致命性胃-主动脉瘘)。

结论

食管支架在吻合口漏和穿孔的治疗中可能发挥重要作用。成功取决于适当的源控制程序和外科医生的经验。

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