Division of Social Psychiatry, Tokyo Institute of Psychiatry, Tokyo Japan.
J Trauma Stress. 2010 Dec;23(6):744-50. doi: 10.1002/jts.20589. Epub 2010 Dec 3.
The authors examined the efficacy of Prolonged Exposure (PE) therapy in Japanese patients with posttraumatic stress disorder (PTSD). Twenty-four patients (21 women, 3 men) with PTSD due to mixed trauma were randomly assigned to the PE group (PE with or without treatment as usual [TAU]) or the control group (TAU) only. The control group received PE after a 10-week period. Intention-to-treat analysis showed the PE group achieved significantly greater reduction than the control group at posttreatment in either PTSD or depressive symptoms. The control group had significantly decreased symptom severity after PE treatment. Symptom levels of 19 PE completers in the both groups remained low in 12-month follow-up assessments. The study's findings will promote the future dissemination and implementation of evidence-based treatment for PTSD in non-Western settings.
作者研究了延长暴露（PE）疗法对日本创伤后应激障碍（PTSD）患者的疗效。24 名 PTSD 患者（21 名女性，3 名男性）因混合创伤被随机分配到 PE 组（PE 加或不加常规治疗[TAU]）或仅接受 TAU 的对照组。对照组在 10 周后接受 PE。意向治疗分析显示，PE 组在治疗后 PTSD 或抑郁症状方面的缓解程度明显大于对照组。对照组在接受 PE 治疗后症状严重程度显著下降。在 12 个月的随访评估中，两组中的 19 名 PE 完成者的症状水平仍然较低。该研究的结果将促进未来在非西方环境中推广和实施 PTSD 的循证治疗。
