Pediatric Pulmonology, State University of New York at Buffalo, Women and Children's Hospital of Buffalo, Buffalo, New York 14222, USA.
Pediatr Pulmonol. 2011 Jan;46(1):92-5. doi: 10.1002/ppul.21306. Epub 2010 Dec 3.
The spectrum of disease with pandemic novel H1N1 influenza A (2009) virus ranges from non-febrile, mild upper respiratory tract infection to severe or fatal pneumonia. We report the bronchoscopic findings associated with a fatal case of H1N1 influenza A associated with co-infection with methicillin-resistant Staphylococcus aureus (MRSA) in a previously healthy child, which were more severe than those previously described as associated with seasonal influenza infection alone. The severity of the airway pathology seen on bronchoscopy in this patient may be due to a unique effect of the H1N1 influenza A virus or may be as a result of a destructive synergism between this virus and bacteria such as MRSA.
新型甲型 H1N1 流感病毒（2009 年）引起的疾病谱范围从无发热、轻度上呼吸道感染到严重或致命性肺炎不等。我们报告了一例与新型甲型 H1N1 流感相关的、合并感染耐甲氧西林金黄色葡萄球菌（MRSA）的致命病例的支气管镜检查结果，该结果比先前描述的单纯季节性流感感染相关的支气管镜检查结果更为严重。该患者支气管镜下气道病变的严重程度可能是由于新型甲型 H1N1 流感病毒的独特作用，也可能是由于该病毒与 MRSA 等细菌之间的破坏性协同作用所致。
