Han Chunjiao, Zhang Tongqiang, Zhao Yidi, Dong Lili, Li Xiaole, Zheng Jiafeng, Guo Wei, Xu Yongsheng, Cai Chunquan
Clinical School of Pediatrics, Tianjin Medical University, Tianjin, China.
Department of Pulmonology, Tianjin Children's Hospital, Tianjin University Children's Hospital, Tianjin, China.
Front Pediatr. 2022 Aug 26;10:959419. doi: 10.3389/fped.2022.959419. eCollection 2022.
With the rapid increase in the number of infections, children with () infection secondary to Influenza A virus (IAV), appear to have a great possibility of causing severe complications and illness. Despite some cases and research findings regarding the death of children with IAV and , coinfection included, there were few details about successful treatment of pleural empyema and necrotizing pneumonia caused by methicillin-resistant (MRSA) infection following IAV. In this case report, we describe the clinical symptoms and treatment of a teenager with pleural empyema and necrotizing pneumonia related to secondary infection who was initially infected by IAV. This case highlights the importance of early recognition and application of thoracoscopy for this potentially fatal pleural empyema caused by MRSA and IAV coinfection. We conclude that this is a significant case that contributes to raising awareness regarding rarely occurring severe respiratory infections by MRSA in a child with normal immune function after IAV. In addition, further studies are needed to explore risk factors for IAV coinfection with .
随着感染数量的迅速增加，甲型流感病毒（IAV）继发感染的儿童似乎极有可能引发严重并发症和疾病。尽管有一些关于包括IAV和（此处原文括号内容缺失）合并感染在内的儿童死亡病例及研究结果，但关于IAV后耐甲氧西林（此处原文缺失相关内容，推测可能是“金黄色葡萄球菌”之类）（MRSA）感染所致胸膜脓胸和坏死性肺炎成功治疗的细节却很少。在本病例报告中，我们描述了一名青少年的临床症状及治疗情况，该青少年最初感染IAV，后发生与（此处原文括号内容缺失）继发感染相关的胸膜脓胸和坏死性肺炎。本病例突出了早期识别并应用胸腔镜治疗由MRSA和IAV合并感染引起的这种潜在致命性胸膜脓胸的重要性。我们得出结论，这是一个重要病例，有助于提高对免疫功能正常的儿童在IAV后发生罕见的MRSA严重呼吸道感染的认识。此外，还需要进一步研究以探索IAV与（此处原文括号内容缺失）合并感染的危险因素。
