Gaillard Raphaël, Loo Henry, Olie Jean-Pierre
Hôpital Sainte Anne, 1, rue Cabanis, 75014 Paris.
Bull Acad Natl Med. 2010 Mar;194(3):567-78; discussion 578-81.
The psychiatrist is confronted by a variety of emotional states, ranging from sadness to exaltation. The term "psychache "has been used to describe depression with melancholic features. But can such mental pain be defined without reference to visible lesions or precise physical symptoms? We report pathophysiological evidence supporting this concept and show that it has implications for both treatment and prognosis. Cognitive studies have shown that the neurological substrate of physical pain is also activated by mental pain. Mental pain is associated with a risk of suicide and can be improved by analgesics, including opiates and ketamine.
精神科医生面临着各种各样的情绪状态，从悲伤到兴奋。“精神痛苦”一词已被用于描述具有忧郁特征的抑郁症。但是，能否在不提及可见病变或确切身体症状的情况下定义这种精神痛苦呢？我们报告了支持这一概念的病理生理学证据，并表明它对治疗和预后都有影响。认知研究表明，身体疼痛的神经学基础也会被精神痛苦激活。精神痛苦与自杀风险相关，并且可以通过包括阿片类药物和氯胺酮在内的镇痛药得到改善。
