[健康男性及患有尖锐湿疣的男性患者阴毛毛囊中人乳头瘤病毒的患病率]

[Prevalence of human papillomavirus in the pubic hair follicles of healthy men and male patients with genital warts].

作者信息

Wang You-bao, Han Tao, Zhao Chun-xiong

机构信息

Department of Urology, Haici Hospital of Qingdao, Qingdao, Shandong 266033, China.

出版信息

Zhonghua Nan Ke Xue. 2010 Sep;16(9):783-5.

PMID:21171259

Abstract

OBJECTIVE

Human papillomavirus (HPV) commonly exists in healthy individuals, but its prevalence in the pubic hair follicles is not yet clear, nor is the relationship between HPV infection in the pubic hair follicles and the recurrence of genital warts in men. This study aimed to investigate HPV infection in the pubic hair follicles of healthy men and patients with genital warts, and to look into the correlation of HPV infection with recurrent genital warts.

METHODS

We included in this study 122 healthy men aged 21-80 years and 86 male patients with genital warts aged 24-61 years, detected HPV in their pubic hair follicles by PCR, and made comparative analysis of the data obtained from the two groups.

RESULTS

The positive rate of HPV in the pubic hair follicles of the healthy males was 17.21% (21/122), including 15 cases of HPV6, 4 HPV11, 1 non-HPV6/11 and 1 the mixed type (both HPV6 and HPV11), while that of the genital wart patients was 32.55% (28/86), including 17 cases of HPV6, 7 HPV11, 2 non-HPV6/11 and 2 the mixed type.

CONCLUSION

The incidence of HPV infection is higher in patients with genital warts than in healthy men, while the types of HPV involved are basically the same in the two groups, mainly HPV6 and HPV11.

摘要

目的

人乳头瘤病毒（HPV）普遍存在于健康个体中，但其在阴毛毛囊中的流行情况尚不清楚，且阴毛毛囊HPV感染与男性尖锐湿疣复发之间的关系也不明确。本研究旨在调查健康男性和尖锐湿疣患者阴毛毛囊中的HPV感染情况，并探究HPV感染与尖锐湿疣复发的相关性。

方法

本研究纳入122名年龄在21 - 80岁的健康男性和86名年龄在24 - 61岁的男性尖锐湿疣患者，通过聚合酶链反应（PCR）检测其阴毛毛囊中的HPV，并对两组所得数据进行比较分析。

结果

健康男性阴毛毛囊中HPV阳性率为17.21%（21/122），其中HPV6型15例，HPV11型4例，非HPV6/11型1例，混合型（HPV6和HPV11均阳性）1例；而尖锐湿疣患者阴毛毛囊中HPV阳性率为32.55%（28/86），其中HPV6型17例，HPV11型7例，非HPV6/11型2例，混合型2例。