Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.
Expert Rev Anti Infect Ther. 2011 Jan;9(1):123-33. doi: 10.1586/eri.10.150.
Neurocysticercosis is an endemic disease in Latin America, Asia and Africa with growing occurrence in industrialized countries due to the increase in migration from low- and middle-income to high-income countries. The most severe clinical presentation is when the parasite is located in the subarachnoid space at the base of the brain (NCSAB). Aside from its clinical presentation, the severity of this form of the disease is due to the difficulties in diagnosis and treatment. Although NCSAB frequency is lower than that reported for the parenchymal location of the parasite, its clinical relevance must be emphasized. We provide a critical review of the central epidemiological, clinical, diagnostic and therapeutic features of this particular form of the disease, which is still associated with unacceptably high rates of morbidity and mortality.
神经囊虫病是拉丁美洲、亚洲和非洲的地方病,由于从中等和低收入国家向高收入国家的移民增加,工业化国家的发病率也在不断上升。寄生虫位于脑基底蛛网膜下腔时(脑底神经囊虫病),临床表现最严重。除临床表现外,这种疾病的严重程度还归因于诊断和治疗的困难。尽管脑底神经囊虫病的发病率低于脑实质部位寄生虫的报道,但必须强调其临床重要性。我们对该病的中央流行病学、临床、诊断和治疗特点进行了批判性回顾,尽管该病的发病率和死亡率仍然高得令人无法接受。