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与神经囊虫病相关的癫痫发作和癫痫:一种分类学建议。

Seizures and Epilepsy in Association With Neurocysticercosis: A Nosologic Proposal.

机构信息

From the Department of Neurology (G.S.), Dayanand Medical College & Hospital, Ludhiana, India; Center for Global Health and School of Sciences (H.H.G.), Universidad Peruana Cayetano Heredia; Cysticercosis Unit (H.H.G.), Instituto Nacional de Ciencaia Neurologicas, Lima, Peru; School of Medicine and Research Center (O.H.D.B.), Universidad Espiritu Santo-Ecuador, Samborondón; Albert Einstein College of Medicine (C.C.), Bronx, NY; Department of Clinical & Experimental Epilepsy (J.W.S.), UCL Queen Square Institute of Neurology, London; and Chalfont Centre for Epilepsy (J.W.S.), Chalfont St Peter, United Kingdom.

出版信息

Neurology. 2024 Nov 12;103(9):e209865. doi: 10.1212/WNL.0000000000209865. Epub 2024 Oct 7.

Abstract

Neurocysticercosis is one of the main risk factors of seizures and epilepsy in many regions of the world, which are -endemic but resource-constrained to control the parasite. The nosology of seizures and the classification of epilepsy in the context of neurocysticercosis are somewhat uncertain. Many seizures associated with the infection are customarily referred to as "acute symptomatic seizures." The term, however, seems unsuitable. Neither is the condition acute nor does it allow the avoidance of long-term antiseizure medications, as is the case with acute symptomatic seizures, for instance, associated with traumatic brain injury. We propose that seizures be classified according to the evolutionary stage of parenchymal cysticercosis in addition to the conventional classification of seizures and epilepsy and identification of the epileptogenic zone. An often-ignored aspect is the identification of comorbidities, many of which are specific to neurocysticercosis.

摘要

脑囊虫病是世界上许多地区癫痫发作和癫痫的主要危险因素之一,这些地区寄生虫病流行,但资源有限,无法控制寄生虫。癫痫发作的分类和脑囊虫病背景下的癫痫分类有些不确定。许多与感染相关的癫痫发作通常被称为“急性症状性癫痫发作”。然而,这个术语似乎并不合适。这种情况既不是急性的,也不允许像与创伤性脑损伤相关的急性症状性癫痫发作那样避免长期抗癫痫药物。我们建议除了常规的癫痫发作和癫痫分类以及致痫区的识别之外,根据实质囊虫病的进化阶段对癫痫发作进行分类。一个经常被忽视的方面是识别合并症,其中许多是神经囊虫病特有的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d1/11460340/a1b3c4fd26d7/WNL-2024-101901f1.jpg

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