Department of Clinical Medicine, University of Bergen, Norway.
J Atten Disord. 2012 May;16(4):339-45. doi: 10.1177/1087054710385784. Epub 2010 Dec 20.
The purpose of this study was to investigate how often drugs used to treat migraine and ADHD are prescribed to the same patients to assess, indirectly, the comorbidity of these disorders.
We used data from the Norwegian prescription database for 2006, including the total Norwegian population (N = 4,640,219).
Antimigraine drugs were prescribed to 81,225 persons (1.75% of the total population), anti-ADHD drugs to 18,481 persons (0.40%), and 284 persons were prescribed both types of drugs. There was a positive and significant association between prescription of antimigraine and anti-ADHD drugs for all age groups between 20 and 50 for both genders, with odds ratios ranging from 1.76 to 2.81.
The prescription patterns for these drugs in adult patients indicate a comorbidity between migraine and ADHD.
本研究旨在调查治疗偏头痛和 ADHD 的药物在多大程度上被开给同一患者,从而间接评估这些疾病的共病情况。
我们使用了 2006 年挪威处方数据库的数据,包括挪威总人口(N=4640219 人)。
有 81225 人(总人口的 1.75%)被开了抗偏头痛药物,18481 人(0.40%)被开了抗 ADHD 药物,有 284 人同时被开了这两种药物。在所有年龄组(20 至 50 岁)中,两性患者的抗偏头痛药物和抗 ADHD 药物的处方之间均存在正相关和显著关联,优势比范围为 1.76 至 2.81。
这些药物在成年患者中的处方模式表明偏头痛和 ADHD 之间存在共病情况。