Lambertus M W, Kwok R Y, Mulligan M E
Medical Service, Sepulveda Veterans Affairs Medical Center, California 91343.
Antimicrob Agents Chemother. 1990 Jul;34(7):1453-5. doi: 10.1128/AAC.34.7.1453.
The in vitro activity of trimethoprim plus dapsone against oxacillin-resistant Staphylococcus aureus was comparable to that of trimethoprim plus sulfamethoxazole. Because of its different pharmacologic properties, dapsone may be a useful agent in combination with trimethoprim for the treatment of patients colonized with oxacillin-resistant S. aureus.
甲氧苄啶加氨苯砜对耐苯唑西林金黄色葡萄球菌的体外活性与甲氧苄啶加磺胺甲恶唑相当。由于其药理特性不同,氨苯砜可能是与甲氧苄啶联合用于治疗耐苯唑西林金黄色葡萄球菌定植患者的有用药物。