Mendelson Asher A, al-Macki Khalil, Chauvin Peter, Kost Karen M
Department of Otolaryngology-Head and Neck Surgery, Montreal General Hospital, McGill University, 1650 Cedar Ave., Suite A2-141, Montreal, QC H3G 1A4, Canada.
Ear Nose Throat J. 2010 Dec;89(12):600-3.
Sclerosing mucoepidermoid carcinoma (SMEC) is an extremely rare variant of mucoepidermoid carcinoma with unique histologic features. To the best of our knowledge, only 14 cases of salivary gland SMEC have been previously reported in the English-language literature since it was discovered in 1987. We report a new case of salivary gland SMEC, and we review the literature. Because of SMEC's distinctive histologic features and rarity, its diagnosis can be difficult. Moreover, no clear treatment strategy has emerged with regard to adjuvant postoperative radiotherapy. We attempt to elucidate a natural course of this disease, and we propose a conservative approach to postoperative management.
硬化性黏液表皮样癌（SMEC）是黏液表皮样癌的一种极其罕见的变异型，具有独特的组织学特征。据我们所知，自1987年发现以来，英文文献中此前仅报道过14例涎腺SMEC。我们报告1例新的涎腺SMEC病例，并对文献进行综述。由于SMEC独特的组织学特征及罕见性，其诊断可能存在困难。此外，关于术后辅助放疗尚无明确的治疗策略。我们试图阐明该疾病的自然病程，并提出一种保守的术后管理方法。
