Högman C F, Eriksson L
Department of Clinical Immunology and Transfusion Medicine, University Hospital, Uppsala, Sweden.
Biomed Biochim Acta. 1990;49(2-3):S198-203.
The changing pattern in transfusion medicine with emphasis on the collection of plasma for fractionation and Factor VIII production, an increased use of platelets, and needs to reduce virus transmission and leukocyte immunogenicity, has made it important to optimize the procedures used in the preparation of blood components. The anticoagulant solution should allow sufficient time between collection and component preparation without considerable loss of quality. Whenever possible, red cells and platelets should be stored in special storage media, thus allowing a maximum volume of plasma to be collected and fractionated into plasma products. Some examples of procedures in current use or under development and their practical and economical consequences are given in this brief review.
输血医学的模式不断变化，重点在于采集血浆用于成分分离和生产凝血因子VIII、增加血小板的使用，以及需要减少病毒传播和白细胞免疫原性，这使得优化血液成分制备过程中使用的程序变得至关重要。抗凝剂溶液应在采集和成分制备之间留出足够的时间，而不会造成质量的显著损失。只要有可能，红细胞和血小板应储存在特殊的储存介质中，从而能够收集最大量的血浆并将其分离成血浆制品。本简要综述给出了一些目前正在使用或正在开发的程序示例及其实际和经济影响。
