Madi José M, Araújo Breno F, Zatti Helen, Rombaldi Renato L, Madi Sônia R C, de Zorzi Patricia, Terres Alana Z, Varisco Bruna B, Berti Isabele R, Dal Sochio Katherine, Bampi Rochele
Obstetric and Gynecology Department, Hospital Geral, Caxias do Sul University, Caxias do Sul, RS, Brazil.
Hypertens Pregnancy. 2012;31(3):350-6. doi: 10.3109/10641955.2010.525279. Epub 2010 Dec 21.
Analyze maternal and perinatal aspects related to chronic hypertension (CH) in pregnancy.
Cross-section and retrospective study. Maternal, obstetric, and neonatal variables inserted in a database of the SPSS program, version 16.0, were analyzed. Student's t-test was applied to the continuous variables and the chi-square test to the dichotomous variables, considering as statistically significant a value of p < 0.05.
From March 1998 to February 2009 about 15,945 births were observed, 888 (5.5%) being related to pregnant mothers with CH. In the hypertense group, there was a higher percentage of cesarean section, preterm labor during pregnancy, abruptio placentae, small-for-gestational age babies (<2500 g), and the need for treatment in a neonatal intensive care unit (NICU).
CH in pregnancy was significantly associated with maternal age ≥30 years, nonwhite race, low level of schooling, parity ≥3 children, weight gain ≥16 kg, greater rates of cesarean section, Apgar score at the first and fifth minutes <7, umbilical artery pH ≤7.1, fetal weight ≤2500 g, need for neonatal intensive care, preterm labor during pregnancy, abruptio placentae, birth injury, small-for-gestational age babies and higher rates of preterm babies, fetal and neonatal mortality. It should be emphasized that the variables mentioned are representative or poor birth conditions in the group of chronic hypertense pregnant women.
分析与妊娠期慢性高血压（CH）相关的孕产妇和围产期情况。
横断面回顾性研究。对录入SPSS 16.0版程序数据库中的孕产妇、产科和新生儿变量进行分析。连续变量采用学生t检验，二分变量采用卡方检验，p<0.05为具有统计学意义。
1998年3月至2009年2月期间共观察到约15945例分娩，其中888例（5.5%）与患有CH的孕妇有关。高血压组剖宫产、孕期早产、胎盘早剥、小于胎龄儿（<2500g）以及新生儿重症监护病房（NICU）治疗需求的比例更高。
妊娠期CH与以下因素显著相关：母亲年龄≥30岁、非白人种族、低教育水平、胎次≥3胎、体重增加≥16kg、剖宫产率更高、第1和第5分钟阿氏评分<7、脐动脉pH≤7.1、胎儿体重≤2500g、新生儿重症监护需求、孕期早产、胎盘早剥、产伤、小于胎龄儿以及早产率更高、胎儿和新生儿死亡率更高。应强调的是，上述变量代表了慢性高血压孕妇群体中不良的出生条件。
