Cai Fei, Gao Weiwei, Li Hongling, Chen Juan, Li Zhizhong
The Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Zhongguo Zhong Yao Za Zhi. 2010 Oct;35(19):2503-7.
The mould phenomenon occurred commonly in the cultivation, processing and storage period of medicinal materials, which may result in production of mycotoxins. Mycotoxin contaminations caused by fungi are major issues related to the quality and safety of Chinese herbal medicine. This review summarized the work published in aflatoxins contamination of Chinese herbal medicine in China through the previous decade. The conclusion to be drawn from this survey is that aflatoxin exposure remains an important aspect of Chinese herbal medicine safety which needs to be paid great attention. We raised some points that should be focused on in future. The strategies of changing environment to suppress growth of toxin-producing fungus, so as to reduce aflatoxins are the most practical and effective ways, while biological control in the field production is a promising approach.
霉变现象在中药材的种植、加工及储存过程中普遍存在，这可能会导致霉菌毒素的产生。由真菌引起的霉菌毒素污染是与中药材质量和安全相关的主要问题。本综述总结了过去十年间国内发表的有关中药材黄曲霉毒素污染的研究。本次调查得出的结论是，黄曲霉毒素暴露仍然是中药材安全的一个重要方面，需要予以高度关注。我们提出了一些未来应重点关注的要点。改变环境以抑制产毒真菌生长从而减少黄曲霉毒素的策略是最切实有效的方法，而田间生产中的生物防治是一种很有前景的途径。
