Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
J Dermatol. 2011 Jan;38(1):41-4. doi: 10.1111/j.1346-8138.2010.01128.x.
One of the recent advances in dermoscopy is the significance of parallel ridge pattern (PRP), which has 99% specificity in detecting both melanoma in situ and advanced melanoma on the acral volar skin. This review features exceptionally benign acral lesions showing PRP on dermoscopy. These benign lesions can be distinguished from malignant melanoma, because of the typical clinical history and associated symptoms. However, it is sometimes difficult for dermatologists to exclude malignant melanoma and a subsequent skin biopsy should be strongly recommended. These benign lesions include pigmentation due to a dye such as para-phenylenediamine, acral pigmented macules associated with Peutz-Jeghers syndrome, anti-cancer drug-induced hyperpigmentation on the volar skin, acral subcorneal hemorrhage and pigmented warts.
近年来，皮肤镜检查的一个进展是平行嵴状模式（PRP）的意义，它在检测肢端掌跖部原位黑素瘤和进展期黑素瘤方面具有 99%的特异性。本综述介绍了在皮肤镜检查下表现出 PRP 的非常良性的肢端病变。这些良性病变可以与恶性黑色素瘤区分开来，因为它们具有典型的临床病史和相关症状。然而，皮肤科医生有时很难排除恶性黑色素瘤，因此强烈建议进行皮肤活检。这些良性病变包括由于对苯二胺等染料引起的色素沉着、与 Peutz-Jeghers 综合征相关的肢端色素斑、掌跖部抗癌药物诱导的色素沉着、肢端皮下出血和色素性疣。
