Department of Public Health, Pierre Fabre, Boulogne, France.
J Eur Acad Dermatol Venereol. 2011 Feb;25 Suppl 1:24-9. doi: 10.1111/j.1468-3083.2010.03899.x.
Atopic dermatitis and psoriasis engender a significant deterioration in patients' quality of life. Although the efficacy of patient management at the Avène hydrotherapy centre has been demonstrated by clinical studies, few data relating to changes in the quality of life following therapeutic management are available. The objective of this study was to evaluate the short- and medium-term effects of hydrotherapy not only on the patients' quality of life, but also on the quality of life of the parents of the treated children.
In this 6-month longitudinal observational study, adult (n = 174) and paediatric (n = 212) atopic patients and psoriatic patients (n = 262) had to complete questionnaires relating to the quality of life at the beginning (D0) and after 3 weeks hydrotherapy (W3), and then, 3 (M3) and 6 months (M6) later. The dermatology life quality index (DLQI) and the Short-Form-12 Health Survey (SF-12) generic questionnaire were given to adult patients. The children's dermatological life quality index (CDLQI) was given to paediatric patients, and the SF-12 to their parents.
At D0, the DLQI score was 29.7 ± 20.1 and 26.9 ± 18.9 for atopic and psoriatic patients, respectively. At W3, this score had decreased significantly to reach 16.8 ± 14.9 (P < 0.01) and 10.0 ± 10.5 (P < 0.001) for atopic and psoriatic patients, respectively. The DLQI scores at M3 and M6 were 20.7 ± 16.4 and 23.1 ± 18.8 for atopic patients and 18.8 ± 16.7 and 21.9 ± 19.6 for psoriatic patients and remained significantly lower in comparison with D0 values (P < 0.05).
A 3-week course of treatment at the Avène hydrotherapy centre significantly improved the quality of life of patients suffering from skin diseases. This improvement persisted 3 and 6 months after management by hydrotherapy.
特应性皮炎和银屑病会显著降低患者的生活质量。虽然临床研究已经证明了阿维尼翁水疗中心对患者管理的疗效，但关于治疗管理后生活质量变化的数据却很少。本研究的目的是评估水疗不仅对患者，而且对接受治疗的儿童的父母的生活质量的短期和中期影响。
在这项为期 6 个月的纵向观察研究中，成人（n=174）和儿科（n=212）特应性患者和银屑病患者（n=262）必须在开始（D0）和 3 周水疗（W3）后以及 3 个月（M3）和 6 个月（M6）后填写与生活质量相关的问卷。成人患者使用皮肤病生活质量指数（DLQI）和 12 项简明健康调查问卷（SF-12）通用问卷。儿科患者使用儿童皮肤病生活质量指数（CDLQI），其父母使用 SF-12。
在 D0 时，特应性和银屑病患者的 DLQI 评分分别为 29.7±20.1 和 26.9±18.9。在 W3 时，这一评分显著下降，分别达到 16.8±14.9（P＜0.01）和 10.0±10.5（P＜0.001）。在 M3 和 M6 时，特应性患者的 DLQI 评分为 20.7±16.4 和 23.1±18.8，银屑病患者的 DLQI 评分为 18.8±16.7 和 21.9±19.6，与 D0 值相比仍显著较低（P＜0.05）。
在阿维尼翁水疗中心进行为期 3 周的治疗显著改善了患有皮肤病患者的生活质量。这种改善在水疗管理后 3 个月和 6 个月仍然持续。
