Kanwal Shamsa, Osman Enass Y, Khiari Imen
Department of Medical, Oral and Biotechnological Sciences, University of Chieti - Pescara "G. d'Annunzio", 66100, Chieti, Italy.
Department of Pharmacology and Toxicology, Tanta University, Tanta, Egypt.
Int J Biometeorol. 2025 May 27. doi: 10.1007/s00484-025-02937-0.
Balneotherapy is a widely accepted and well-practiced treatment modality for dermatological diseases in many countries worldwide. The use of balneotherapy approaches for skin disease management is continuously increasing, but the mechanism by which thermal water affects the treatment of different dermatological conditions has not been fully explored. This comprehensive review seeks to consolidate scientific findings regarding the effects of thermal water in the treatment of different skin diseases, such as psoriasis, atopic dermatitis, acne, ichthyosis, and lichen planus, as well as its cosmeceutical effects, drawing from both in vitro and in vivo research. This review analyzed both in vitro and in vivo studies to validate the anti-inflammatory, immunomodulatory, and antioxidant potential of thermal water in dermatology. Thermal water exhibits these properties, making it beneficial for treating various skin conditions and enhancing cosmeceutical effects." Many studies have strongly demonstrated the therapeutic benefits of different thermal waters for the successful treatment of many skin diseases, and these materials have been incorporated into cosmetics for skin hydration and anti-aging and anti-wrinkle effects. The physicochemical and microbial characteristics of thermal water contribute to its therapeutic properties, with sulfurous water being particularly effective due to their favorable mineral composition and antioxidative effects.Although the cosmetic properties of thermal water are well described, further research is needed to identify specific mineral and microbial profiles for incorporation into cosmetic products and to integrate advanced technologies and approaches to increase the effectiveness of formulated products. Should aim to clarify the underlying mechanisms of action of thermal waters, investigate optimal treatment protocols, and assess their long-term efficacy. Longitudinal clinical trials are also needed to assess the long-term benefits and safety of these treatments, paving the way for standardized protocols in dermatological care.
在世界许多国家，浴疗法是一种广泛被接受且应用广泛的皮肤病治疗方式。将浴疗法应用于皮肤病管理的情况在不断增加，但温泉水影响不同皮肤病治疗的机制尚未得到充分探索。这篇综述旨在整合关于温泉水对不同皮肤病（如银屑病、特应性皮炎、痤疮、鱼鳞病和扁平苔藓）治疗效果的科学发现，以及其美容功效，这些发现来自体外和体内研究。这篇综述分析了体外和体内研究，以验证温泉水在皮肤病学中的抗炎、免疫调节和抗氧化潜力。温泉水具有这些特性，使其有利于治疗各种皮肤疾病并增强美容效果。许多研究有力地证明了不同温泉水对成功治疗多种皮肤病的治疗益处，并且这些物质已被纳入化妆品中以实现皮肤保湿以及抗老化和抗皱效果。温泉水的物理化学和微生物特性有助于其治疗特性，含硫温泉水因其有利的矿物质成分和抗氧化作用而特别有效。尽管温泉水的美容特性已有充分描述，但仍需要进一步研究以确定可纳入化妆品的特定矿物质和微生物特征，并整合先进技术和方法以提高配方产品的有效性。应旨在阐明温泉水的潜在作用机制，研究最佳治疗方案，并评估其长期疗效。还需要进行纵向临床试验以评估这些治疗的长期益处和安全性，为皮肤病护理的标准化方案铺平道路。
