Barcelona Centre for International Health Research (CRESIB), Hospital Clínic / IDIBAPS, Universitat de Barcelona, Spain.
Malar J. 2010 Dec 22;9:369. doi: 10.1186/1475-2875-9-369.
Building on previous acceptability research undertaken in sub-Saharan Africa this article aims to investigate the acceptability of intermittent preventive treatment of malaria in infants (IPTi) in Papua New Guinea (PNG).
A questionnaire was administered to mothers whose infants participated in the randomised placebo controlled trial of IPTi. Mothers whose infants participated and who refused to participate in the trial, health workers, community reporters and opinion leaders were interviewed. Men and women from the local community also participated in focus group discussions.
Respondents viewed IPTi as acceptable in light of wider concern for infant health and the advantages of trial participation. Mothers reported complying with at-home administration of IPTi due to perceived benefits of IPTi and pressure from health workers. In spite of patchy knowledge, respondents also demonstrated a demand for infant vaccinations and considered non-vaccination to be neglect. There is little evidence that IPTi has negative impacts on attitudes to EPI, EPI adherence or existing malaria prevention practices.
The degree of similarity between findings from the acceptability studies undertaken in sub-Saharan Africa and PNG allows some generalization relating to the implementation of IPTi outside of Africa: IPTi fits well with local health cultures, appears to be accepted easily and has little impact on attitudes towards EPI or malaria prevention. The study adds to the evidence indicating that IPTi could be rolled out in a range of social and cultural contexts.
本文基于在撒哈拉以南非洲进行的先前可接受性研究，旨在调查在巴布亚新几内亚（PNG）中婴儿间歇性预防治疗疟疾（IPTi）的可接受性。
对参加 IPTi 随机安慰剂对照试验的婴儿的母亲进行了问卷调查。对参加试验但拒绝参加试验的母亲、卫生工作者、社区记者和意见领袖进行了访谈。当地社区的男性和女性也参加了焦点小组讨论。
受访者认为 IPTi 是可以接受的，因为他们更关心婴儿的健康，并且认为参与试验有好处。母亲们报告说，由于认为 IPTi 有好处并且受到卫生工作者的压力，她们在家中遵守 IPTi 的管理。尽管知识参差不齐，但受访者也表现出对婴儿疫苗接种的需求，并认为不接种疫苗是忽视。几乎没有证据表明 IPTi 对 EPI 的态度、EPI 的依从性或现有的疟疾预防措施有负面影响。
在撒哈拉以南非洲和 PNG 进行的可接受性研究的结果非常相似，这使得我们可以在一定程度上对非洲以外地区实施 IPTi 进行概括：IPTi 非常适合当地的卫生文化，似乎很容易被接受，并且对 EPI 或疟疾预防的态度影响很小。这项研究增加了表明 IPTi 可以在一系列社会和文化背景下推出的证据。
