AlAnezi Amer Z, Zhu Qiang, Wang Yu-Hsiung, Safavi Kamran E, Jiang Jin
Division of Endodontology, School of Dental Medicine, University of Connecticut Health Center, Farmington, CT 06030-1715, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Jan;111(1):122-7. doi: 10.1016/j.tripleo.2010.07.013.
Various additives have been suggested to be used with mineral trioxide aggregate (MTA) to improve its handling characteristics. The purpose of this study was to evaluate the effects of various additives on setting time and cell attachment on gray MTA (GMTA).
Single-rooted caries-free teeth were split, and dentin disks with class I cavity were made and filled with test and control materials. Setting time was measured using Gilmore apparatus. Mouse MC3T3-E1 osteoblasts and L929 mouse fibroblasts were grown on dentin and GMTA disks. Cell attachment was examined under fluorescent microscope.
Adding KY liquid, CaCl(2), and NaOCl to GMTA improved the handling properties and decreased setting time. Osteoblasts and fibroblasts attached and spread on GMTA mixed with additives in a manner similar to GMTA mixed with water.
The various additives could be possible substitutes to water to decrease MTA setting time. MTA is biocompatible when mixed with the various additives.
有人建议使用各种添加剂与三氧化矿物凝聚体（MTA）混合，以改善其操作性能。本研究的目的是评估各种添加剂对灰色MTA（GMTA）凝固时间和细胞黏附的影响。
将单根无龋牙劈开，制作带有I类洞的牙本质片，并用测试材料和对照材料填充。使用吉尔摩仪测量凝固时间。将小鼠MC3T3-E1成骨细胞和L929小鼠成纤维细胞培养在牙本质和GMTA片上。在荧光显微镜下检查细胞黏附情况。
向GMTA中添加KY液、CaCl₂和NaOCl可改善其操作性能并缩短凝固时间。成骨细胞和成纤维细胞以与GMTA与水混合时类似的方式附着并铺展在与添加剂混合的GMTA上。
各种添加剂可能是水的替代品，可缩短MTA凝固时间。MTA与各种添加剂混合时具有生物相容性。
