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不停跳与传统二尖瓣手术

Beating heart versus conventional mitral valve surgery.

作者信息

Babaroglu Seyhan, Yay Kerem, Parlar Ali Ihsan, Ates Can, Mungan Ufuk, Cicekcioglu Ferit, Tutun Ufuk, Katircioglu Salih Fehmi

机构信息

Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Hospital, Sihhiye, 06100 Ankara, Turkey.

出版信息

Interact Cardiovasc Thorac Surg. 2011 Mar;12(3):441-7. doi: 10.1510/icvts.2010.255240. Epub 2010 Dec 21.

Abstract

OBJECTIVES

The present study aimed to compare the results of beating heart technique and conventional mitral valve surgery (MVS).

METHODS

Three hundred and nineteen patients who underwent MVS between April 2005 and December 2006 were enrolled in the study. While 125 patients underwent beating heart MVS (group 1), the conventional approach was used for 194 patients (group 2). Of those patients who underwent beating heart MVS, 75 underwent MVS without cross-clamping the aorta. Coronary sinus retroperfusion was used during surgery in the remaining 50 patients. The right anterolateral thoracotomy was performed in nine out of the 29 patients requiring re-operation, while resternotomy was performed in 20.

RESULTS

No significant differences were shown between the groups in the preoperative period in terms of the Parsonnet mortality score, Ontario mortality score, and length of intensive care stay. However, there were significant differences with respect to EuroSCORE risk score, EuroSCORE mortality, and Parsonnet risk score, and length of hospital stay according to Ontario risk scoring. It was established that the patients in group 1 had a shorter length of hospital stay [group 1: six days (range, 4-37 days); group 2: 10 days (range, 4-62 days)]. Group 1 was observed to have shorter time periods when the groups were compared regarding operative time [group 1: 130 min (range, 100-270 min); group 2: 240 min (range, 100-360 min)], cross-clamping (XCL) time [group 1: 27.5 min (range, 3-99 min); group 2: 60.5 min (range, 30-163 min)], and cardiopulmonary bypass time [group 1: 57 min (range, 22-150 min); group 2: 90 min (range, 39-388 min)]. There were also significant differences in favor of group 1 in terms of postoperative need for inotropic support [group 1: 26 patients (16%); group 2: 68 patients (35%)]. Although there were no statistically significant differences in the groups in terms of mortality rates according to the Parsonnet scoring system, with the exception of the moderate risk group, it was noted that the mortality rates in the beating heart group were lower.

CONCLUSIONS

This study concluded that beating heart MVS can be performed successfully, particularly for patients at higher risk which will lead to increased morbidity and mortality in postoperative period.

摘要

目的

本研究旨在比较心脏跳动技术与传统二尖瓣手术(MVS)的结果。

方法

选取2005年4月至2006年12月期间接受二尖瓣手术的319例患者纳入研究。其中125例患者接受心脏跳动二尖瓣手术(第1组),194例患者采用传统手术方式(第2组)。在接受心脏跳动二尖瓣手术的患者中,75例在不阻断主动脉的情况下进行二尖瓣手术。其余50例患者在手术期间采用冠状静脉窦逆行灌注。29例需要再次手术的患者中有9例采用右前外侧开胸手术,20例采用胸骨正中切开术。

结果

在术前阶段,两组在Parsonnet死亡率评分、安大略死亡率评分和重症监护住院时间方面无显著差异。然而,在欧洲心脏手术风险评估系统(EuroSCORE)风险评分、EuroSCORE死亡率、Parsonnet风险评分以及根据安大略风险评分的住院时间方面存在显著差异。结果显示第1组患者的住院时间较短[第1组:6天(范围4 - 37天);第2组:10天(范围4 - 62天)]。比较两组的手术时间[第1组:130分钟(范围100 - 270分钟);第2组:240分钟(范围100 - 360分钟)]、阻断(XCL)时间[第1组:27.5分钟(范围3 - 99分钟);第2组:60.5分钟(范围30 - 163分钟)]和体外循环时间[第1组:57分钟(范围22 - 150分钟);第2组:90分钟(范围39 - 388分钟)]时,第1组的时间也较短。在术后对血管活性药物支持的需求方面,第1组也显著优于第2组[第1组:26例患者(16%);第2组:68例患者(35%)]。根据Parsonnet评分系统,除中度风险组外,两组在死亡率方面无统计学显著差异,但注意到心脏跳动组的死亡率较低。

结论

本研究得出结论,心脏跳动二尖瓣手术可以成功进行,特别是对于高风险患者,这类患者术后发病率和死亡率会增加。

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