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煤矿工人中的肺气肿和慢性阻塞性肺疾病。

Emphysema and chronic obstructive pulmonary disease in coal miners.

机构信息

Division of Pulmonary and Critical Care Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

出版信息

Curr Opin Pulm Med. 2011 Mar;17(2):123-5. doi: 10.1097/MCP.0b013e3283431674.

Abstract

PURPOSE OF REVIEW

Coal mining remains a major industry that has workers at risk for developing chronic lung disease. Aside from simple coal workers' pneumoconiosis and progressive massive fibrosis, the development of emphysema and obstructive lung disease independent of smoking may be underappreciated. This article reviews more recent studies that may help rectify this faulty view.

RECENT FINDINGS

Cumulative exposure to coal dust is a significant risk factor for the development of emphysema and has an additive effect to smoking. Increased coal dust exposure is associated with increased risk of death from chronic obstructive pulmonary disease (COPD). In newly employed coal miners, bronchitic symptoms are associated with a rapid decline in lung function within 2 years after starting work. In evaluating impairment, the chest radiograph may be helpful as a marker of exposure but the diffusing capacity is most correlated with dyspnea, whereas the emphysema computed tomography score has good association with expiratory flow limitation.

SUMMARY

Latest studies further support the association of emphysema and COPD with coal dust exposure. Increased cumulative exposure may also increase risk of death from these diseases.

摘要

目的综述

采煤仍是一个高危行业,其工人有罹患慢性肺部疾病的风险。除了单纯的煤工尘肺和进行性大块纤维化,肺气肿和与吸烟无关的阻塞性肺部疾病的发展可能被低估了。本文回顾了一些有助于纠正这一错误观点的最新研究。

最近的发现

煤炭粉尘的累计暴露是肺气肿发展的一个重要危险因素,并且与吸烟有相加作用。增加的煤炭粉尘暴露与慢性阻塞性肺疾病(COPD)死亡风险增加有关。在新入职的煤矿工人中,在开始工作后 2 年内,出现支气管炎症状与肺功能快速下降有关。在评估损伤时,胸部 X 线可能有助于作为暴露的标志物,但弥散能力与呼吸困难相关性最好,而肺气肿 CT 评分与呼气流量受限有良好的相关性。

总结

最新研究进一步支持了肺气肿和 COPD 与煤炭粉尘暴露的关联。累计暴露量的增加也可能增加这些疾病的死亡风险。

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