Institute of Chemical and Engineering Sciences, No. 1 Pesek Road, Jurong Island 627833, Singapore.
Molecules. 2010 Dec 21;15(12):9437-49. doi: 10.3390/molecules15129437.
This review covers the application of cycloaddition reactions in forming the boron-containing compounds such as symmetric star-shaped boron-enriched dendritic molecules, nano-structured boron materials and aromatic boronic esters. The resulting boron compounds are potentially important reagents for both materials science and medical applications such as in boron neutron capture therapy (BNCT) in cancer treatment and as drug delivery agents and synthetic intermediates for carbon-carbon cross-coupling reactions. In addition, the use of boron cage compounds in a number of cycloaddition reactions to synthesize unique aromatic species will be reviewed briefly.
本文综述了环加成反应在合成含硼化合物中的应用，如对称星形富硼树枝状分子、纳米结构硼材料和芳香硼酸酯。所得的硼化合物是材料科学和医学应用中潜在的重要试剂，如硼中子俘获治疗（BNCT）在癌症治疗中的应用，以及作为药物传递剂和碳-碳交叉偶联反应的合成中间体。此外，还简要综述了硼笼化合物在一些环加成反应中合成独特芳香族化合物的应用。
