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应激性心肌病

Takotsubo cardiomyopathy.

作者信息

Arroja José D, Urban Philip

机构信息

Cardiovascular Department, La Tour Hospital, Geneva, Switzerland.

出版信息

Indian Heart J. 2010 Jan-Feb;62(1):68-71.

PMID:21180038
Abstract

Takotsubo cardiomyopathy is a cardiac dysfunction characterized by transient segmented ballooning of the left ventricle, usually the apical region. It mainly affects postmenopausal women and represents 1 to 2% of all cases of suspected myocardial infarction. Clinical presentation is similar to that of an acute coronary syndrome, with chest pain and dyspnea as the main symptoms. Cardiac biomarkers and ECG are unable to differentiate Takotsubo from myocardial infarction. The diagnosis is suggested by the coexistence ofabnormal regional left ventricle kinetics, often severe, together with the absence of significant coronary disease. MRI imaging may be useful to confirm the diagnosis. Management mainly focuses on stabilising the patient's hemodynamics during the acute phase. Prognosis is usually excellent, and complete recovery of cardiac function is the norm. We report five cases of Takotsubo cardiomyopathy recently seen in our institution and review the literature.

摘要

应激性心肌病是一种心脏功能障碍,其特征为左心室,通常是心尖区域出现短暂的节段性膨出。它主要影响绝经后女性,占疑似心肌梗死病例的1%至2%。临床表现与急性冠状动脉综合征相似,主要症状为胸痛和呼吸困难。心脏生物标志物和心电图无法将应激性心肌病与心肌梗死区分开来。左心室局部动力学异常(通常较为严重)且无明显冠状动脉疾病可提示诊断。磁共振成像(MRI)可能有助于确诊。治疗主要集中在急性期稳定患者的血流动力学。预后通常良好,心脏功能完全恢复是常态。我们报告了最近在我们机构中见到的5例应激性心肌病病例并对文献进行了综述。

相似文献

1
Takotsubo cardiomyopathy.应激性心肌病
Indian Heart J. 2010 Jan-Feb;62(1):68-71.
2
[Takotsubo cardiomyopathy mimicking an acute myocardial infarction].[酷似急性心肌梗死的应激性心肌病]
Med Klin (Munich). 2008 Jun 15;103(6):441-4. doi: 10.1007/s00063-008-1063-6.
3
Takotsubo cardiomyopathy: case report and review of the literature.应激性心肌病:病例报告及文献综述
Proc West Pharmacol Soc. 2008;51:48-51.
4
Takotsubo cardiomyopathy or myocardial infarction? Answers from delayed enhancement magnetic resonance imaging.应激性心肌病还是心肌梗死?延迟强化磁共振成像给出答案。
Int J Cardiol. 2009 Jun 12;135(1):e9-12. doi: 10.1016/j.ijcard.2008.03.025. Epub 2008 Jul 1.
5
Apical ballooning syndrome or Takotsubo cardiomyopathy: a new challenge in acute cardiac care.心尖气球样变综合征或应激性心肌病:急性心脏护理中的新挑战。
Cardiol J. 2008;15(6):572-7.
6
Takotsubo cardiomyopathy, or broken-heart syndrome.应激性心肌病,又称心碎综合征。
Ann Pharmacother. 2010 Mar;44(3):590-3. doi: 10.1345/aph.1M568. Epub 2010 Feb 2.
7
Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction.心尖气球样变综合征(Tako-Tsubo综合征或应激性心肌病):急性心肌梗死的一种模仿疾病。
Am Heart J. 2008 Mar;155(3):408-17. doi: 10.1016/j.ahj.2007.11.008. Epub 2008 Jan 31.
8
[Takotsubo cardiomyopathy; reversible cardiomyopathy induced by stress].[应激性心肌病;由压力诱发的可逆性心肌病]
Ned Tijdschr Geneeskd. 2009;153:B363.
9
[Broken heart syndrome or Takotsubo cardiomyopathy. (Literature review and clinical observations)].[心碎综合征或应激性心肌病。(文献综述与临床观察)]
Ter Arkh. 2010;82(9):72-7.
10
Transient left ventricular ballooning syndrome.一过性左心室球囊样综合征。
Eur J Intern Med. 2009 Sep;20(5):454-6. doi: 10.1016/j.ejim.2008.12.001. Epub 2009 Jan 30.