Arroja José D, Urban Philip
Cardiovascular Department, La Tour Hospital, Geneva, Switzerland.
Indian Heart J. 2010 Jan-Feb;62(1):68-71.
Takotsubo cardiomyopathy is a cardiac dysfunction characterized by transient segmented ballooning of the left ventricle, usually the apical region. It mainly affects postmenopausal women and represents 1 to 2% of all cases of suspected myocardial infarction. Clinical presentation is similar to that of an acute coronary syndrome, with chest pain and dyspnea as the main symptoms. Cardiac biomarkers and ECG are unable to differentiate Takotsubo from myocardial infarction. The diagnosis is suggested by the coexistence ofabnormal regional left ventricle kinetics, often severe, together with the absence of significant coronary disease. MRI imaging may be useful to confirm the diagnosis. Management mainly focuses on stabilising the patient's hemodynamics during the acute phase. Prognosis is usually excellent, and complete recovery of cardiac function is the norm. We report five cases of Takotsubo cardiomyopathy recently seen in our institution and review the literature.
应激性心肌病是一种心脏功能障碍,其特征为左心室,通常是心尖区域出现短暂的节段性膨出。它主要影响绝经后女性,占疑似心肌梗死病例的1%至2%。临床表现与急性冠状动脉综合征相似,主要症状为胸痛和呼吸困难。心脏生物标志物和心电图无法将应激性心肌病与心肌梗死区分开来。左心室局部动力学异常(通常较为严重)且无明显冠状动脉疾病可提示诊断。磁共振成像(MRI)可能有助于确诊。治疗主要集中在急性期稳定患者的血流动力学。预后通常良好,心脏功能完全恢复是常态。我们报告了最近在我们机构中见到的5例应激性心肌病病例并对文献进行了综述。