Liao Peng, Zhang Yong, Liao Yue, Zheng Nian-jun, Zhang Xu
Shan Dong Institute of Physical Education and Sports, Jinan 250063, China.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2007 Nov;23(4):491-4.
To investigate the effects of CoQlo supplementation on liver mitochondrial function and aerobic capacity in adolescent athletes.
Based on a single blinded study design, 18 male adolescent swimming athletes were randomized into two groups, supplement CoQ10 100 mg/d (Q group), or placebo (P group) for 28 days respectively.
(1) After supplementation, the plasma CoQ10 concentration in Q group was significantly elevated and significantly higher compared to P group. (2) After supplementation, the rest plasma MDA level in Q group remained unchanged and was significantly lower compared to P group. (3) The plasma CoQ10 concentration of the 18 athletes was significantly decreased during the first constant endurance exercise. (4) The baseline plasma CoQ10 of the 18 subjects showed significantly positive correlation with VO2max measured in the first incremental exercise. (5) No significant difference of increased level of AKBR between Q group and P group. (6) No significant difference of increase level of VO2max, individual lactate threshold and exercise economy between Q and P group.
Although there is an increased demand for plasma CoQ10 during endurance exercise and CoQ10 supplement can depress lipid peroxidation, there is no effect of CoQ10 supplementation on liver mitochondrial function and aerobic capacity in adolescent athletes.
探讨补充辅酶Q10对青少年运动员肝脏线粒体功能和有氧能力的影响。
基于单盲研究设计，将18名男性青少年游泳运动员随机分为两组，分别补充辅酶Q10 100mg/d（Q组）或安慰剂（P组），为期28天。
（1）补充后，Q组血浆辅酶Q10浓度显著升高，且显著高于P组。（2）补充后，Q组静息血浆丙二醛水平无变化，且显著低于P组。（3）18名运动员在第一次持续耐力运动期间血浆辅酶Q10浓度显著降低。（4）18名受试者的基线血浆辅酶Q10与第一次递增运动中测得的最大摄氧量呈显著正相关。（5）Q组和P组之间AKBR升高水平无显著差异。（6）Q组和P组之间最大摄氧量、个体乳酸阈和运动经济性的增加水平无显著差异。
尽管耐力运动期间对血浆辅酶Q10的需求增加，且补充辅酶Q10可抑制脂质过氧化，但补充辅酶Q10对青少年运动员的肝脏线粒体功能和有氧能力没有影响。
