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[心血管手术期间用于脑监测的近红外光谱技术]

[Near Infrared Spectroscopy for cerebral monitoring during cardiovascular surgery].

作者信息

La Monaca M, David A, Gaeta R, Lentini S

机构信息

Cardiovascular and Thoracic Department, Policlinico G. Martino Hospital, University of Messina, Viale Gazzi, Messina, Italy.

出版信息

Clin Ter. 2010;161(6):549-53.

PMID:21181086
Abstract

Near-infrared spectroscopy (NIRS) is an optical imaging technique for medical applications, able to monitor the variation of hemoglobin saturation into the tissues. The NIR photon passes through the biological tissue following a path similar to a more or less complex split. The NIR absorption of photons is proportional to the concentration of chromophores (pigments that absorb the light in the spectral region of interest). NIRS probes are used as the light source on the same side of the source receiver, being this last able to capture the photons after their journey into the tissues. The NIRS methodology may be applied as an imaging technique for various organs. In this review the authors describe the use of NIRS for the continuous monitoring of regional cerebral oxygen saturation in the course of cardiovascular surgical procedures. Thanks to the NIRS technique, changes in cerebral oximetry can be monitored continuously during cardiovascular surgery. A desaturation greater than 20% of baseline or an rSO2 absolute value less than 50%, are associated with a reduction of the cortical somatosensory evoked potentials and an increase of neurological damage and / or cognitive impairment. During carotid surgery, reduction and / or asymmetries of rSO2 value are encountered in the course of intraoperative clamping causing cerebral hypoperfusion. Instead, rSO2 increase may predict hyperperfusion syndrome after carotid stenting or endarterectomy. Cerebral hyperperfusion syndrome is rare, but often fatal once it has established. The NIRS may represent an added value in those patients. The NIRS is also applied during surgery performed with cardiopulmonary bypass, including aortic arch surgery with cardiocirculatory arrest. Continuous monitoring of any changes in cerebral rSO2 allows a rapid treatment in the aim to improve the psycho-neurological outcome of patients undergoing this type of surgery.

摘要

近红外光谱(NIRS)是一种用于医学应用的光学成像技术,能够监测组织中血红蛋白饱和度的变化。近红外光子通过生物组织时所遵循的路径类似于或多或少复杂的分支。光子的近红外吸收与发色团(在感兴趣的光谱区域吸收光的色素)的浓度成正比。NIRS探头用作光源和接收器同侧的光源,接收器能够在光子进入组织传播后捕获它们。NIRS方法可作为各种器官的成像技术应用。在这篇综述中,作者描述了在心血管外科手术过程中使用NIRS连续监测局部脑氧饱和度的情况。得益于NIRS技术,在心血管手术期间可以连续监测脑血氧饱和度的变化。饱和度下降超过基线的20%或rSO2绝对值低于50%,与皮层体感诱发电位降低以及神经损伤和/或认知障碍增加有关。在颈动脉手术期间,术中夹闭过程中会出现rSO2值降低和/或不对称,导致脑灌注不足。相反,rSO2升高可能预示颈动脉支架置入术或动脉内膜切除术后的高灌注综合征。脑高灌注综合征很少见,但一旦发生往往致命。NIRS可能对这些患者具有附加价值。NIRS也应用于体外循环手术,包括心脏停搏的主动脉弓手术。连续监测脑rSO2的任何变化有助于快速治疗,以改善接受此类手术患者的心理神经学预后。

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