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近红外光谱在营养干预研究中的应用。

The application of near infrared spectroscopy in nutritional intervention studies.

机构信息

Faculty of Health and Life Sciences, Brain, Performance and Nutrition Research Centre, Northumbria University Newcastle upon Tyne, UK.

出版信息

Front Hum Neurosci. 2013 Aug 13;7:473. doi: 10.3389/fnhum.2013.00473. eCollection 2013.

Abstract

Functional near infrared spectroscopy (NIRS) is a non-invasive optical imaging technique used to monitor cerebral blood flow (CBF) and by proxy neuronal activation. The use of NIRS in nutritional intervention studies is a relatively novel application of this technique, with only a small, but growing, number of trials published to date. These trials-in which the effects on CBF following administration of dietary components such as caffeine, polyphenols and omega-3 polyunsaturated fatty acids are assessed-have successfully demonstrated NIRS as a sensitive measure of change in hemodynamic response during cognitive tasks in both acute and chronic treatment intervention paradigms. The existent research in this area has been limited by the constraints of the technique itself however advancements in the measurement technology, paired with studies endeavoring increased sophistication in number and locations of channels over the head should render the use of NIRS in nutritional interventions particularly valuable in advancing our understanding of the effects of nutrients and dietary components on the brain.

摘要

功能性近红外光谱(NIRS)是一种非侵入性的光学成像技术,用于监测脑血流(CBF)和间接监测神经元激活。NIRS 在营养干预研究中的应用是该技术的一个相对较新的应用,迄今为止,只有少数但不断增加的试验已经发表。这些试验——评估了饮食成分(如咖啡因、多酚和ω-3 多不饱和脂肪酸)给药后对 CBF 的影响——成功地证明了 NIRS 是一种在急性和慢性治疗干预范式中评估认知任务期间血液动力学反应变化的敏感测量方法。然而,该领域的现有研究受到该技术本身的限制,随着测量技术的进步,以及研究努力增加头部通道数量和位置的复杂性,NIRS 在营养干预中的应用特别有价值,可以帮助我们深入了解营养物质和饮食成分对大脑的影响。

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