Schiefer W, Hasenbein B, Schmidt H
Acta Neurochir (Wien). 1978;42(1-2):89-95. doi: 10.1007/BF01406634.
Although multicentric glioblastomas are relatively rare, their occurrence is not an extreme rarity. A multicentric lesion should always be thought of when the symptoms cannot be related to a single focus and when the special investigations do not confirm a single lesion. In our opinion the brain scintigram and the computer tomogram offer the best diagnostic possibilities at present. If the preoperative diagnosis has been made, then an indication for operation can be justified only if multiple tumours can be removed through one approach and, what is even more important, at one sitting. The cases demonstrated prove that this procedure can be successful. If, on the other hand, only one of several tumours is excised, then a fatal outcome is almost certain.
虽然多中心性胶质母细胞瘤相对罕见，但并非极其罕见。当症状无法归因于单一病灶且特殊检查未证实为单一病灶时，应始终考虑多中心性病变。我们认为，脑闪烁图和计算机断层扫描目前提供了最佳的诊断可能性。如果已做出术前诊断，那么只有当多个肿瘤可以通过一种入路切除，而且更重要的是，能一次性切除时，手术指征才是合理的。所展示的病例证明这一手术方法是可以成功的。另一方面，如果只切除了几个肿瘤中的一个，那么几乎肯定会导致致命的结果。
