Meyer S, Ptok M
Klinik für Phoniatrie und Pädaudiologie, Medizinische Hochschule Hannover, MHH. OE 6510, 30623, Hannover, Germany.
HNO. 2011 Jan;59(1):68-72. doi: 10.1007/s00106-010-2236-1.
Swallowing as a neurophysiological process has recently attracted much interest. Knowledge of cortical involvement in particular has raised hope that a novel form of dysphagia therapy might be possible by means of cortical stimulation.
For this systematic review a selective literature research in PubMed has been carried out.
The cortex is not only involved in the initiation of swallowing, but also during pharyngeal and esophageal phases. In addition, there appears to be a hemispheric dominance both for swallowing and its individual phases.
In light of recent study results, the theory of the pattern generators' autonomy must be abandoned, since pattern generators seem to be influenced rather by the cortex. During the recovery of unilateral impairments, the intact hemisphere seems to play a significant role due to cortical reorganisation processes. Several studies indicate that repetitive transcranial stimulation, and thereby modulation of cortical areas as a means of dysphagia therapy, could be beneficial.
吞咽作为一种神经生理过程,近来备受关注。尤其是关于皮质参与的知识,让人燃起了通过皮质刺激实现新型吞咽困难治疗方法的希望。
为进行本系统评价,在PubMed上开展了选择性文献研究。
皮质不仅参与吞咽的启动,还参与咽部和食管期。此外,吞咽及其各个阶段似乎都存在半球优势。
鉴于近期研究结果,必须摒弃模式发生器自主性的理论,因为模式发生器似乎更多地受皮质影响。在单侧功能障碍的恢复过程中,由于皮质重组过程,完整的半球似乎发挥着重要作用。多项研究表明,重复经颅刺激,进而通过调节皮质区域作为吞咽困难治疗的一种手段,可能是有益的。