Smit J C, de Vaal J B
Departement Kritieke Sorg, Universiteit van die Oranje-Vrystaat, Bloemfontein.
S Afr Med J. 1990 Sep 1;78(5):254-7.
A study was undertaken to show that the determination of glomerular filtration rate with radio-labelled sodium chromate ethylenediaminetetra-acetic acid is a repeatable, easily performed and accurate examination in the critically ill patient. Differences in glomerular filtration rate were relatively small, with a phase difference of between -10,59 and 5,34. Creatinine clearance showed a greater variation over a corresponding period, with a difference of between -27,50 and -4,10. The study indicated that this method of determining glomerular filtration rate can be very useful in an intensive care unit, because it seems to be more accurate and easier to perform. Information is obtained more quickly than when the glomerular filtration rate is determined by means of creatinine clearance.
一项研究旨在表明,用放射性标记的乙二胺四乙酸铬酸钠测定肾小球滤过率,对于危重症患者来说是一项可重复、操作简便且准确的检查。肾小球滤过率的差异相对较小,相差在-10.59至5.34之间。肌酐清除率在相应时间段内变化更大,相差在-27.50至-4.10之间。该研究表明,这种测定肾小球滤过率的方法在重症监护病房可能非常有用,因为它似乎更准确且操作更简便。与通过肌酐清除率测定肾小球滤过率相比,能更快地获得信息。