People Eye Center, Peking University People's Hospital, and Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China.
J Cataract Refract Surg. 2011 Jan;37(1):77-82. doi: 10.1016/j.jcrs.2010.07.029.
To assess and compare the morphologic changes in the anterior segment in eyes with nuclear or cortical age-related cataract using Scheimpflug imaging.
Peking University People's Hospital, Beijing, China.
Case-control study.
Patients with nuclear or cortical age-related cataract were recruited. The grade of nuclear opalescence or cortical opacity was assessed using the Lens Opacities Classification System III (LOCS III). A group of elderly subjects with a clear lens and normal vision served as the control group. Anterior chamber depth (ACD), anterior chamber volume (ACV), and lens thickness were evaluated using Scheimpflug imaging (Pentacam).
Two hundred sixty-nine patients (330 eyes) were recruited. Thirty eyes were enrolled for each nuclear opalescence and cortical grade. The control group comprised 30 eyes (19 subjects). In eyes with age-related cataract, lens thickness increased with an increase in cortical opacity, whereas the ACD and ACV values decreased. The ACD was inversely correlated with LOCS III grades for nuclear opalescence (r = -0.197, P = .004), nuclear color (r = -0.195, P = .005), and cortical opacity (r = -0.508, P<.005). There were significant differences in lens thickness, ACD, and ACV between nuclear color, nuclear opalescence, and cortical opacity for LOCS III grades 3, 4, and 5, respectively.
There were significant differences in lens thickness, ACD, and ACV between nuclear and cortical age-related cataracts. The ACD decreased more in eyes with cortical cataract, suggesting that the risk for angle-closure glaucoma may be greater in cases of cortical opacity in which lens expansion is greater.
No author has a financial or proprietary interest in any material or method mentioned.
使用 Scheimpflug 成像评估和比较核性或皮质性年龄相关性白内障患者眼前节的形态变化。
中国北京北京大学人民医院。
病例对照研究。
招募核性或皮质性年龄相关性白内障患者。使用 Lens Opacities Classification System III (LOCS III) 评估核混浊或皮质混浊程度。一组晶状体透明且视力正常的老年受试者作为对照组。使用 Scheimpflug 成像（Pentacam）评估前房深度（ACD）、前房容积（ACV）和晶状体厚度。
共招募 269 例患者（330 只眼）。核混浊和皮质各等级各纳入 30 只眼。对照组包括 30 只眼（19 名受试者）。在年龄相关性白内障眼中，晶状体厚度随皮质混浊程度的增加而增加，而 ACD 和 ACV 值则降低。ACD 与核混浊的 LOCS III 等级呈负相关（r = -0.197，P =.004）、核颜色（r = -0.195，P =.005）和皮质混浊（r = -0.508，P<.005）。核颜色、核混浊和皮质混浊的 LOCS III 等级 3、4 和 5 时，晶状体厚度、ACD 和 ACV 之间存在显著差异。
核性和皮质性年龄相关性白内障的晶状体厚度、ACD 和 ACV 存在显著差异。皮质性白内障眼 ACD 下降更为明显，提示在晶状体扩张更大的皮质混浊病例中，闭角型青光眼的风险可能更大。
无作者在文中提及的任何材料或方法中具有财务或专有利益。
