Miles Center for Pediatric Ophthalmology, Storm Eye Institute, Department of Ophthalmology, MedicalUniversity of South Carolina, Charleston, South Carolina 29425-5536, USA.
J Cataract Refract Surg. 2011 Jan;37(1):83-7. doi: 10.1016/j.jcrs.2010.07.036.
To report the incidence of visual axis opacification (VAO) requiring surgery after cataract extraction with hydrophobic acrylic intraocular lens (IOL) implantation during the first year of life.
Storm Eye Institute, Charleston, South Carolina, USA; Iladevi Cataract and IOL Research Center, Ahmedabad, India.
Cohort study.
Medical records of patients younger than 1 year who had primary posterior capsulectomy, vitrectomy, and in-the-bag hydrophobic acrylic IOL implantation were reviewed. In bilateral cases, 1 eye was randomly chosen. The need for surgery for visually significant VAO was evaluated 12 months after cataract surgery.
Seventy-two eyes were included. The mean age at cataract surgery was 6.0 months. Seventeen eyes (23.6%) required surgery for VAO a mean of 6.2 ± 2.9 months postoperatively. The odds for VAO surgery were 3.5 times greater in eyes of female children than in eyes of male children. For AcrySof MA60AC, SA60AT, SN60AT, or SN60WF IOLs, surgery for VAO was required in 25%, 23%, 23%, and 23% of eyes, respectively. The earliest time between cataract and secondary VAO surgery was relatively later (9.0 months) with the SN60WF IOL than with the MA60AC, SA60AT, or SN60AT IOL (4.4, 2.2, and 2.0 months, respectively).
Nearly 25% of operated eyes of infants required a secondary surgical procedure for VAO; the rate was higher in eyes of female infants but did not differ between IOL models. The data indicate that surgery for VAO is required later in eyes with an SN60WF IOL than in eyes in which other AcrySof IOLs were used.
No author has a financial or proprietary interest in any material or method mentioned.
报告在出生后第一年行白内障摘除术联合疏水性丙烯酸人工晶状体（IOL）植入术后需要手术治疗的视觉轴混浊（VAO）的发生率。
美国南卡罗来纳州查尔斯顿市 Storm Eye 研究所；印度艾哈迈达巴德 Iladevi 白内障和 IOL 研究中心。
队列研究。
回顾了行后囊膜切开术、玻璃体切除术和囊袋内疏水性丙烯酸 IOL 植入术的年龄小于 1 岁的患者的病历资料。对于双侧病例，随机选择 1 只眼。术后 12 个月评估因 VAO 导致的视力显著下降而需要手术的情况。
72 只眼纳入研究。白内障手术的平均年龄为 6.0 个月。17 只眼（23.6%）术后平均 6.2±2.9 个月需要手术治疗 VAO。女性患儿眼发生 VAO 手术的可能性是男性患儿眼的 3.5 倍。对于 AcrySof MA60AC、SA60AT、SN60AT 或 SN60WF IOL，VAO 手术分别在 25%、23%、23%和 23%的眼中进行。白内障和继发性 VAO 手术之间的最早时间相对较晚（9.0 个月），与 MA60AC、SA60AT 或 SN60AT IOL 相比，与 SN60WF IOL 相比（分别为 4.4、2.2 和 2.0 个月）。
近 25%接受手术的婴儿眼需要二次手术治疗 VAO；女性婴儿眼的发生率较高，但不同 IOL 模型之间无差异。数据表明，与使用其他 AcrySof IOL 的眼相比，SN60WF IOL 眼发生 VAO 后需要进行手术的时间较晚。
无作者在提及的任何材料或方法中具有财务或专有利益。
