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瑞典国家儿童白内障登记处术后视网膜脱离和细菌性眼内炎的发病率及相关危险因素

Incidence of postoperative retinal detachment and bacterial endophthalmitis in the Swedish national paediatric cataract register and associated risk factors.

作者信息

Karatepe Hashas Arzu Seyhan, Linnarsson Wiklund Anna, Gyllén Jenny, Haargaard Birgitte, Magnusson Gunilla, Nyström Alf, Tornqvist Kristina, Trocmé Eric, Kjellström Ulrika

机构信息

Department of Ophthalmology, Region Västra Götaland, Sahlgrenska University Hospital, Mölndal, Sweden.

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

出版信息

Acta Ophthalmol. 2025 Aug;103(5):561-570. doi: 10.1111/aos.17460. Epub 2025 Feb 14.

Abstract

PURPOSE

To investigate the incidence and risk factors of retinal detachment (RD) and bacterial endophthalmitis in a cohort of children who underwent cataract surgery before the age of eight.

METHODS

Data was retrieved from the Swedish national paediatric cataract register. All eyes with congenital or infantile cataract that underwent surgery between January 1, 2007, and December 31, 2023 with at least one follow-up were included. Cases associated with trauma, uveitis or RD at surgery were excluded. Parameters that could be important for complications were analysed.

RESULTS

RD was found in seven of 1073 eyes reflecting an incidence of 0.65%. There were no statistically significant differences in age at surgery, presences of intellectual disability or general disease, cataract type, surgical technique, axial length, corneal diameter, previous glaucoma surgery or occurrence of persistent fetal vasculature (PFV), although the frequency of glaucoma surgery and PFV was higher in RD cases; 42.9% versus 13.2% and 57.1% versus 26.0%. Aphakia was significantly more common in RD patients; 71.4% versus 19.3% (p = 0.042), as well secondary glaucoma; 57.1% versus 19.5% (p = 0.032). No cases of endophthalmitis were observed.

CONCLUSION

The incidence of RD was low compared to previous studies and no endophthalmitis was found. This might be a result of centralized paediatric cataract care with few but experienced surgeons. Aphakia and secondary glaucoma were associated with higher RD risk and those cases should be followed carefully. PFV and glaucoma surgery were found at a higher frequency in RD cases prompting comprehensive postoperative care also for these children.

摘要

目的

调查8岁前接受白内障手术的儿童队列中视网膜脱离(RD)和细菌性眼内炎的发生率及危险因素。

方法

数据取自瑞典国家儿童白内障登记处。纳入2007年1月1日至2023年12月31日期间接受手术且至少有一次随访的所有先天性或婴儿性白内障患眼。排除与手术时创伤、葡萄膜炎或RD相关的病例。分析可能对并发症有重要影响的参数。

结果

在1073只眼中发现7只发生RD,发生率为0.65%。手术年龄、智力残疾或全身性疾病的存在、白内障类型、手术技术、眼轴长度、角膜直径、既往青光眼手术或持续性胎儿血管系统(PFV)的发生情况在统计学上无显著差异,尽管RD病例中青光眼手术和PFV的发生率较高;分别为42.9%对13.2%以及57.1%对26.0%。无晶状体在RD患者中显著更常见;分别为71.4%对19.3%(p = 0.042),继发性青光眼也是如此;分别为57.1%对19.5%(p = 0.032)。未观察到眼内炎病例。

结论

与既往研究相比,RD的发生率较低,且未发现眼内炎。这可能是由于儿科白内障护理集中化,手术医生少但经验丰富。无晶状体和继发性青光眼与较高的RD风险相关,应对这些病例进行密切随访。在RD病例中发现PFV和青光眼手术的频率较高,提示也应对这些儿童进行全面的术后护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae62/12235676/2301d741ccba/AOS-103-561-g001.jpg

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