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基层医疗中的心力衰竭患者:老龄化、合并症与多重用药

[Heart failure patients in Primary Care: aging, comorbidities and polypharmacy].

作者信息

Galindo Ortego Gisela, Esteve Inés Cruz, Gatius Jordi Real, Santiago Leonardo Galván, Lacruz Carmen Monsó, Soler Plácido Santafé

机构信息

CAP Primer de Maig, Lleida, España.

出版信息

Aten Primaria. 2011 Feb;43(2):61-7. doi: 10.1016/j.aprim.2010.03.021. Epub 2010 Dec 22.

Abstract

OBJECTIVE

To assess heart failure prevalence, epidemiology, co-morbidities and polypharmacy in our region from electronic patient records. To evaluate gender differences in heart failure patients.

DESIGN

Descriptive, cross-sectional study.

SETTING

Primary care Lleida (Spain).

PARTICIPANTS

All patients from 21 primary care centers with the diagnosis of heart failure in medical records were included.

MAIN OUTCOME MEASUREMENTS

Demographic data, comorbidities and therapeutical subgroups in patients with a diagnosis of heart failure in their clinical record.

RESULTS

Heart failure was found in 0.99% (3017 from 306229 patients), of whom 59% were women, and a mean age of 80 years. Comorbidities: hypertension 67%, diabetes 30%, hyperlipidemia 26.5%, obesity 27%, ischemic heart disease 19%, stroke 11%, atrial fibrillation 31%, COPD 26%, renal failure 12%. Hypertension, hyperlipidemia and obesity were more frequent in women, COPD, ischemic heart disease and renal failure in men. There were no differences in diabetes, stroke and atrial fibrillation. Patients were prescribed a median of 8 different therapeutic subgroups (P25=6 and P75=11). Women were more frequently prescribed diuretics (76%), cardiac glycosides (22%) and ACE inhibitors/angiotensin II receptor antagonists, and men ACE inhibitors/angiotensin II receptor antagonists in combination with beta-blockers.

CONCLUSIONS

Heart failure patients in primary care are elderly, with significant co-morbidities and treated with a high number of drugs. Gender differences exist in cardiovascular risk factors, co-morbidities, and also in therapy.

摘要

目的

通过电子病历评估我们地区心力衰竭的患病率、流行病学、合并症及联合用药情况。评估心力衰竭患者的性别差异。

设计

描述性横断面研究。

地点

西班牙莱里达初级医疗保健机构。

参与者

纳入21个初级医疗保健中心病历诊断为心力衰竭的所有患者。

主要观察指标

临床记录中诊断为心力衰竭患者的人口统计学数据、合并症及治疗亚组。

结果

心力衰竭患者占0.99%(306229例患者中有3017例),其中59%为女性,平均年龄80岁。合并症:高血压67%,糖尿病30%,高脂血症26.5%,肥胖27%,缺血性心脏病19%,中风11%,心房颤动31%,慢性阻塞性肺疾病(COPD)26%,肾衰竭12%。高血压、高脂血症和肥胖在女性中更常见,COPD、缺血性心脏病和肾衰竭在男性中更常见。糖尿病、中风和心房颤动无差异。患者平均开具8种不同治疗亚组的药物(第25百分位数=6,第75百分位数=11)。女性更常使用利尿剂(76%)、强心苷(22%)和ACE抑制剂/血管紧张素II受体拮抗剂,男性则更常使用ACE抑制剂/血管紧张素II受体拮抗剂联合β受体阻滞剂。

结论

初级医疗保健中的心力衰竭患者年龄较大,合并症严重,且用药种类多。心血管危险因素、合并症及治疗方面均存在性别差异。

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