Robinson D M, Scrimger J W
Cross Cancer Institute, Edmonton, Alberta, Canada.
Med Dosim. 1990 Jun;15(2):51-9. doi: 10.1016/0958-3947(90)90034-f.
The introduction of an attenuating medium into a photon beam serves both to reduce the intensity of the primary beam and to create secondary radiation due to scatter. When retracted missing tissue compensators are employed to compensate for irregular surface contour or internal inhomogeneities, they are often fabricated without regard to the scattered radiation that they introduce into the system. The study of a mathematically describable conical geometry has clearly demonstrated the need for improved compensator design. Experimental results obtained with this geometry can be reproduced with good agreement, using theoretical calculations based on primary and first order scattered radiation. This method of analysis may be extended to predict the shape of a compensator which will produce an optimized dose distribution at a given depth in a phantom, equivalent to that which would be obtained when an irregular surface is filled with unit density material (bolus), producing a flat surface. An optimized compensator was constructed based on these theoretical considerations and excellent agreement was observed between theory and experiment. Dramatic improvement in the restoration of bolus dose is obtained with this optimized compensator. Finally, an anthropomorphic phantom of the neck region has been constructed and the performance of a compensator designed according to current clinical methods for this geometry has been evaluated. The performance of an optimized compensator specific to this geometry is presented and good agreement between theoretical predictions and experimental results is observed. Dramatic improvement in bolus dose restoration over that obtained with the clinically designed compensator is realized.
在光子束中引入衰减介质既可以降低原射线束的强度,又会因散射产生二次辐射。当采用收缩式组织缺损补偿器来补偿不规则的表面轮廓或内部不均匀性时,其制作往往未考虑到引入系统中的散射辐射。对一种可用数学描述的锥形几何结构的研究清楚地表明了改进补偿器设计的必要性。利用基于原射线和一阶散射辐射的理论计算,可以很好地再现用这种几何结构获得的实验结果。这种分析方法可扩展用于预测补偿器的形状,该补偿器能在模体中给定深度处产生优化的剂量分布,等同于用单位密度材料(填充物)填充不规则表面形成平面时所获得的剂量分布。基于这些理论考虑构建了一个优化补偿器,理论与实验结果吻合良好。使用这种优化补偿器可显著改善填充物剂量的恢复情况。最后,构建了一个颈部区域的仿真人体模体,并评估了根据当前临床方法针对该几何结构设计的补偿器的性能。展示了针对该几何结构的优化补偿器的性能,理论预测与实验结果吻合良好。与临床设计的补偿器相比,填充物剂量恢复情况有显著改善。