[The effect of haptoglobin on prostaglandin H synthase from ram vesicular glands].
作者信息
Murzagalieva A T, Beĭsembaeva R U, Igumnova N D, Mevkh A T
出版信息
Biokhimiia. 1990 May;55(5):791-5.
PMID:2118388
Abstract
It was shown that the ability of sheep and horse haptoglobins differing in their immunological properties to inhibit PGH synthetase is about the same. It was found that haptoglobin inhibits the PGH synthetase-catalyzed enzymatic reaction, the inhibiting effect being non-competitive with respect to the electron donor, adrenaline. The degree of PGH synthetase inhibition by haptoglobin depends on the glycoprotein concentration, incubation time and enzyme activity.
摘要
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