[Identification of haptoglobin as an endogenous inhibitor of prostaglandin H synthetase in the cytosol of sheep vesicular gland cells].
作者信息
Beĭsembaeva R U, Murzagalieva A T, Dzhumalieva L M, Mevkh A T
出版信息
Biokhimiia. 1990 Dec;55(12):2261-7.
PMID:2129019
Abstract
It was shown that sheep vesicular gland cytosol inhibits the peroxidase activity of prostaglandin H synthetase (PGHS). The degree of enzyme inactivation depends on cytosol concentration and incubation time. It was found that cytosol contains a glycoprotein, haptoglobin, which is one of the cytosolic basic components responsible for its ability to inhibit PGHS. Haptoglobin is supposed to participate in endogenous regulation of the PGHS activity in sheep vesicular glands.
摘要
相似文献
1
[Identification of haptoglobin as an endogenous inhibitor of prostaglandin H synthetase in the cytosol of sheep vesicular gland cells].
Biokhimiia. 1990 Dec;55(12):2261-7.
2
Identification of haptoglobin as an endogenous inhibitor of prostaglandin H synthase in the cytosol fraction of primary cells from sheep vesicular glands.
FEBS Lett. 1990 Aug 20;269(1):125-7. doi: 10.1016/0014-5793(90)81135-b.
3
[The effect of haptoglobin on prostaglandin H synthase from ram vesicular glands].
Biokhimiia. 1990 May;55(5):791-5.
4
Cyclooxygenase inactivation kinetics during reaction of prostaglandin H synthase-1 with peroxide.
Biochemistry. 2003 Nov 25;42(46):13772-7. doi: 10.1021/bi035415m.
5
[Mechanisms of interaction of acetylsalicylic acid and indomethacin with endoperoxide prostaglandin synthetase].
Farmakol Toksikol. 1983 Sep-Oct;46(5):44-8.
6
[2-component inhibition of prostaglandin H synthetase by nonsteroidal anti-inflammatory preparations].
Farmakol Toksikol. 1987 Jan-Feb;50(1):46-9.
7
Inhibition of prostaglandin synthase activity of sheep seminal vesicular gland by human serum haptoglobin.
Mol Cell Biochem. 1983;51(2):141-7. doi: 10.1007/BF00230400.
8
[Inactivation of prostaglandin H synthase from sheep vesicular glands with acetylenic fatty acids].
Bioorg Khim. 1993 May;19(5):548-54.
9
Design, synthesis, and biochemical evaluation of N-substituted maleimides as inhibitors of prostaglandin endoperoxide synthases.
J Med Chem. 1996 Apr 12;39(8):1692-703. doi: 10.1021/jm950872p.
10
Effect of 4'-chloro-5-methoxy-3-biphenylylacetic acid (DKA-9) on prostaglandin synthetase.
Arzneimittelforschung. 1980;30(7):1074-6.
Zotero 插件