Department of Surgery, Kuma Hospital, 8-2-35 Shimoyamate-Dori, Chuo-Ku, Kobe, 650-0011 Hyogo, Japan.
World J Surg. 2011 Mar;35(3):558-62. doi: 10.1007/s00268-010-0907-4.
In the present study, we reviewed our experience with thyroid cytological findings showing benign or follicular tumor and evaluated the outcomes in patients who had undergone immediate or late surgical treatment.
In 2007, 445 patients underwent initial surgical therapy for benign or follicular thyroid nodules according to our criteria for surgical indication. Of these, 320 patients underwent thyroid excision immediately. In the remaining 125 patients, surgery was performed after follow-up for more than 18 months.
In this series, the frequencies of finding thyroid carcinoma pathologically were 11.6 and 6.4% in patients undergoing immediate and late surgery, respectively. In these 445 patients, there was no significant difference in age, tumor size, serum thyroglobulin, or nodule growth rate between benign and malignant thyroid nodules. There was, however, a significant difference in ultrasonographic classification.
Our criteria for surgical indication of nodules diagnosed as cytological benign or follicular tumors were considered appropriate. Ultrasonographic evaluation is an important and useful basis for therapeutic decision making in choosing either immediate surgery or observation for cytologically diagnosed benign or follicular tumors.
在本研究中，我们回顾了甲状腺细胞学检查结果为良性或滤泡性肿瘤的患者的经验，并评估了接受即刻或延迟手术治疗患者的结局。
2007 年，根据我们的手术适应证标准，445 例患者因良性或滤泡性甲状腺结节接受了初始手术治疗。其中 320 例患者立即行甲状腺切除术。在其余 125 例患者中，在随访超过 18 个月后进行了手术。
在本系列中，行即刻手术和延迟手术的患者中甲状腺癌的病理检出率分别为 11.6%和 6.4%。在这 445 例患者中，良性和恶性甲状腺结节之间在年龄、肿瘤大小、血清甲状腺球蛋白或结节生长速度方面无显著差异。然而，在超声分类方面存在显著差异。
我们对细胞学诊断为良性或滤泡性肿瘤的结节的手术适应证标准被认为是合适的。超声评估是对细胞学诊断为良性或滤泡性肿瘤的患者选择即刻手术或观察的治疗决策的重要且有用的依据。
