青少年进食障碍：症状与摄食行为中枢控制的相关性。
Eating disorders in adolescents: correlations between symptoms and central control of eating behavior.
机构信息
Post Graduate Program of Nutrition, Federal University of São Paulo, Paulista Medicine School--UNIFESP-EPM, São Paulo/SP, Brazil.
出版信息
Eat Behav. 2011 Jan;12(1):78-82. doi: 10.1016/j.eatbeh.2010.09.008. Epub 2010 Oct 1.
The aim of this study was to verify the relationship between eating disorders (binge eating and bulimia nervosa) and body image dissatisfaction with BMI, anorexigenic and orexigenic factors in adolescents. Thirty-two adolescents, (13 obese [BMI=36.65±5.68] and 19 non-obese [BMI=22.18±3.11]), aged between 14 and 19y, were recruited. Symptoms of eating disorders were measured by self-report questionnaires (BSQ, BITE and BES). Hormones, cytokines and neuropeptides were determined by Elisa kits (Phoenix peptide). A positive correlation was found between: leptin and BES (r=.724), BSQ (r=.705) and BITE (r=.696); BMI and BES (r=.663), BSQ (r=.525) and BITE (r=.732); the same pattern was observed to insulin and TNF-α. A negative correlation was found in α-MSH and AgRP with BES, BSQ and BITE. Blood levels of hormones and neuropeptides could be the link between obesity and eating disorders in adolescents. However, it is not clear which is the cause and which is the consequence.
本研究旨在验证青少年的饮食障碍（暴食症和神经性贪食症）与身体意象不满与 BMI、厌食和食欲因素之间的关系。招募了 32 名青少年，（13 名肥胖[BMI=36.65±5.68]和 19 名非肥胖[BMI=22.18±3.11]），年龄在 14 至 19 岁之间。通过自我报告问卷（BSQ、BITE 和 BES）测量饮食障碍症状。通过 Elisa 试剂盒（凤凰肽）测定激素、细胞因子和神经肽。发现瘦素与 BES（r=.724）、BSQ（r=.705）和 BITE（r=.696）呈正相关；BMI 与 BES（r=.663）、BSQ（r=.525）和 BITE（r=.732）呈正相关；胰岛素和 TNF-α 也呈现出相同的模式。α-MSH 和 AgRP 与 BES、BSQ 和 BITE 呈负相关。激素和神经肽的血液水平可能是青少年肥胖和饮食障碍之间的联系。然而，目前尚不清楚哪个是原因，哪个是结果。
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