Kumaran S, Deivasigamani B, Alagappan K M, Sakthivel M
CAS in Marine Biology, Annamalai University, Parangipettai - 608 502, India.
J Environ Biol. 2010 Jul;31(4):539-41.
Vibriosis is one of the most prevalent fish diseases caused by bacteria belonging to the genus Vibrio sp. Fish disease will be controlled by proper vaccination trials and maintenance of fish form. Pathogenicity for Asian seabass (Lates calcarifer) against V anguillarum results in necrosis and haemorrhagic areas near the base of fins, exopthalmia and ulcers on the skin surface. Around 50, 100, 200 microl of formalin killed bacterial cells were injected (Intraperitoneal) to three different size (5-10, 20-30, 35-50 g) of seabass fishes respectively and control sere as saline were maintained separately. The Relative Percentage Survival (RPS) for vaccinated fishes was 60, 75, and 62.5 respectively and the vaccinations for 20-30 g fishes stay alive. These results stated that the vaccination for fishes with 20-30 g size may fabricate good immune response.
弧菌病是由弧菌属细菌引起的最常见的鱼类疾病之一。鱼类疾病将通过适当的疫苗接种试验和保持鱼的形态来控制。鳗弧菌对尖吻鲈（尖吻鲈）的致病性导致鳍基部附近出现坏死和出血区域、眼球突出以及皮肤表面溃疡。分别向三种不同大小（5 - 10克、20 - 30克、35 - 50克）的尖吻鲈腹腔注射约50、100、200微升福尔马林灭活细菌细胞，同时单独设置注射生理盐水的对照组。接种疫苗的鱼的相对存活率（RPS）分别为60%、75%和62.5%，且20 - 30克的鱼接种疫苗后存活。这些结果表明，对20 - 30克大小的鱼进行疫苗接种可能会产生良好的免疫反应。
