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A low-incidence red cell antigen JAL associated with two unusual Rh gene complexes.

作者信息

Lomas C, Poole J, Salaru N, Redman M, Kirkley K, Moulds M, McCreary J, Nicholson G S, Hustinx H, Green C

机构信息

Medical Research Council Blood Group Unit, London, UK.

出版信息

Vox Sang. 1990;59(1):39-43. doi: 10.1111/j.1423-0410.1990.tb02112.x.

Abstract

A multilaboratory investigation during several years has identified a low incidence antigen JAL on the red cells of 7 propositi. JAL appears to be associated with two unusual Rh complexes, one of which produces a depressed C antigen and the other a depressed c antigen. Family studies strongly suggest that the JAL antigen is encoded by the RH locus. Anti-JAL has been implicated in haemolytic disease of the newborn and is thus considered to be a clinically significant antibody.

摘要

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