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A low-incidence red cell antigen JAL associated with two unusual Rh gene complexes.

作者信息

Lomas C, Poole J, Salaru N, Redman M, Kirkley K, Moulds M, McCreary J, Nicholson G S, Hustinx H, Green C

机构信息

Medical Research Council Blood Group Unit, London, UK.

出版信息

Vox Sang. 1990;59(1):39-43. doi: 10.1111/j.1423-0410.1990.tb02112.x.

DOI:10.1111/j.1423-0410.1990.tb02112.x
PMID:2118698
Abstract

A multilaboratory investigation during several years has identified a low incidence antigen JAL on the red cells of 7 propositi. JAL appears to be associated with two unusual Rh complexes, one of which produces a depressed C antigen and the other a depressed c antigen. Family studies strongly suggest that the JAL antigen is encoded by the RH locus. Anti-JAL has been implicated in haemolytic disease of the newborn and is thus considered to be a clinically significant antibody.

摘要

相似文献

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引用本文的文献

1
Red cells from the original JAL+ proband are also DAK+ and STEM+.来自最初 JAL+先证者的红细胞也是 DAK+和 STEM+。
Vox Sang. 2011 Jul;101(1):61-4. doi: 10.1111/j.1423-0410.2010.01465.x. Epub 2011 Apr 8.
2
JAL (RH48) blood group antigen: serologic observations.JAL(RH48)血型抗原:血清学观察
Transfusion. 2009 Apr;49(4):719-24. doi: 10.1111/j.1537-2995.2008.02025.x. Epub 2008 Dec 15.
3
The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp.JAL抗原(RH48)是由编码精氨酸114色氨酸的RHCE发生变化所致。
Transfusion. 2009 Apr;49(4):725-32. doi: 10.1111/j.1537-2995.2008.02034.x. Epub 2008 Dec 23.
4
Alloanti-c in a c-positive, JAL-positive patient.一名C阳性、JAL阳性患者体内的同种抗 - c。
Vox Sang. 2009 Apr;96(3):240-3. doi: 10.1111/j.1423-0410.2008.01135.x. Epub 2008 Dec 5.